INT78707

Context Info Confidence 0.05 First Reported 1998 Last Reported 2008 Negated 0 Speculated 0 Reported most in Abstract Documents 3 Total Number 3 Disease Relevance 1.43 Pain Relevance 0.77

endoplasmic reticulum (Ksr1) kinase activity (Ksr1) cytoplasm (Ksr1)

Ksr1 (Mus musculus)

Pain Link Frequency Relevance Heat agonist 22 96.16 stellate ganglion block 7 92.32 Pain 1 25.00 headache 1 25.00 Inflammation 6 5.00 cINOD 2 5.00 antagonist 1 5.00

Disease Link Frequency Relevance Heat Cancer 25 99.78 Apoptosis 2 96.88 Breast Cancer 7 95.64 Colon Cancer 10 91.72 Thyroid Neoplasm 2 81.36 Hepatitis B Virus Infection 2 79.20 Polyps 4 77.04 Hepatitis 6 75.00 Ganglion Cysts 1 70.68 Malignant Neoplastic Disease 1 62.16

Sentences Mentioned In

Key:

Protein

Mutation

Event

Anatomy

Negation

Speculation

Pain term

Disease term

There were significant increases in rSO2 and Hb I in the blocked side and decreases in rSO2 and Hb I in the contralateral side.

Negative_regulation (decreases) of Hb I

1) Confidence 0.05 Published 1998 Journal Masui Section Abstract Doc Link 9834598 Disease Relevance 0.07 Pain Relevance 0.57

tumors through a reduction of cyclin D1 and HB-EGF [54] and an increase of p27Kip1 [55–57].

Negative_regulation (reduction) of HB-EGF associated with cancer

2) Confidence 0.02 Published 2008 Journal PPAR Research Section Body Doc Link PMC2430014 Disease Relevance 1.14 Pain Relevance 0.20

Of these, 11 failed to complete the study (4 on Hepacare and 7 on Recombivax-HB); however all but 2 (1 to receive the triple antigen vaccine and 1 to receive Recombivax-HB) were included in the intent-to-treat population for efficacy evaluation.

Negative_regulation (receive) of Recombivax-HB

3) Confidence 0.01 Published 2001 Journal J. Med. Virol. Section Abstract Doc Link 11424117 Disease Relevance 0.22 Pain Relevance 0

General Comments

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