INT78719

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Context Info
Confidence 0.41
First Reported 1998
Last Reported 2010
Negated 1
Speculated 0
Reported most in Body
Documents 8
Total Number 8
Disease Relevance 8.93
Pain Relevance 4.50

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

transport (Ucp1) mitochondrion (Ucp1) transmembrane transport (Ucp1)
Anatomy Link Frequency
central nervous system 1
Ucp1 (Mus musculus)
Pain Link Frequency Relevance Heat
Angina 334 100.00 Very High Very High Very High
Lasting pain 51 100.00 Very High Very High Very High
depression 54 99.40 Very High Very High Very High
alcohol 23 99.10 Very High Very High Very High
Pain 63 96.04 Very High Very High Very High
Central nervous system 2 96.04 Very High Very High Very High
nud 1 93.32 High High
abdominal pain 6 86.88 High High
tolerance 2 84.56 Quite High
Pain threshold 1 75.00 Quite High
Disease Link Frequency Relevance Heat
Angina 328 100.00 Very High Very High Very High
Pain 113 100.00 Very High Very High Very High
Prolapse 56 100.00 Very High Very High Very High
Anxiety Disorder 70 99.76 Very High Very High Very High
Depression 63 99.40 Very High Very High Very High
Nicotine Addiction 39 98.92 Very High Very High Very High
Stress 78 98.70 Very High Very High Very High
Hypertension 30 98.56 Very High Very High Very High
Diabetes Mellitus 27 97.88 Very High Very High Very High
Attention Deficit Hyperactivity Disorder 6 97.72 Very High Very High Very High

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
Gastroenterologists are often consulted in the evaluation of these patients because esophageal disorders are among the most common conditions associated with UCP.
UCP Binding (associated) of associated with angina
1) Confidence 0.41 Published 2001 Journal Am. J. Gastroenterol. Section Abstract Doc Link 11316212 Disease Relevance 1.12 Pain Relevance 0.70
A sedentary lifestyle was also significantly associated with UCP after adjustment for age, smoking, hypertension and diabetes (OR 2.9 (1.7–4.9) and 2.0 (1.1–3.7) for men and women respectively).
UCP Binding (associated) of associated with angina, nicotine addiction, diabetes mellitus and hypertension
2) Confidence 0.40 Published 2008 Journal BMC Public Health Section Body Doc Link PMC2416450 Disease Relevance 2.25 Pain Relevance 0.92
Results showed little spontaneous recovery, and indicated no association between duration of UCP and interest in treatment.
UCP Neg (no) Binding (association) of associated with angina
3) Confidence 0.31 Published 1998 Journal J Psychosom Res Section Abstract Doc Link 9835242 Disease Relevance 0.70 Pain Relevance 0.77
The prevention and reduction of perinatal morbidity and mortality associated with UCP depends on making antenatal care services readily and easily available in areas where they are most needed.
UCP Binding (associated) of associated with prolapse
4) Confidence 0.31 Published 2010 Journal International Journal of Women's Health Section Body Doc Link PMC2971738 Disease Relevance 0.80 Pain Relevance 0.04
Among men, perceived stress at work emerged as the only psychosocial variable significantly associated with UCP.



UCP Binding (associated) of associated with stress and angina
5) Confidence 0.30 Published 2008 Journal BMC Public Health Section Abstract Doc Link PMC2416450 Disease Relevance 1.48 Pain Relevance 0.56
Furthermore, UCP patients, both men and women, reported lower alcohol consumption, an unexpected finding, because UCP is associated with anxiety, depression and impaired mental well-being, which, in turn, is a risk for high alcohol consumption [20].
UCP Binding (associated) of associated with angina, depression, anxiety disorder and alcohol
6) Confidence 0.30 Published 2008 Journal BMC Public Health Section Body Doc Link PMC2416450 Disease Relevance 1.29 Pain Relevance 0.59
The presence of disruptive disorders, in our study ADHD and ODD, is in line with the population-based finding that disruptive disorders are part of the psycho-pathology associated with UCP [17].
UCP Binding (associated) of associated with lasting pain and attention deficit hyperactivity disorder
7) Confidence 0.10 Published 2010 Journal Eur Child Adolesc Psychiatry Section Body Doc Link PMC3012208 Disease Relevance 0.97 Pain Relevance 0.36
Taken together, these results indicate that UCP2, a mitochondrial uncoupling protein previously associated with peripheral energy expenditure, is involved in the mediation of acute ethanol exposure on the central nervous system.
mitochondrial uncoupling protein Binding (associated) of in central nervous system associated with central nervous system
8) Confidence 0.09 Published 2002 Journal Biochem. Pharmacol. Section Abstract Doc Link 12147287 Disease Relevance 0.33 Pain Relevance 0.57

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