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Context Info
Confidence 0.25
First Reported 1998
Last Reported 2008
Negated 0
Speculated 0
Reported most in Body
Documents 4
Total Number 4
Disease Relevance 1.45
Pain Relevance 0.55

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

cytosol (PLA2G4A) aging (PLA2G4A) Golgi apparatus (PLA2G4A)
endoplasmic reticulum (PLA2G4A) cytoplasmic membrane-bounded vesicle (PLA2G4A) nucleus (PLA2G4A)
Anatomy Link Frequency
chondrocytes 1
PLA2G4A (Homo sapiens)
Pain Link Frequency Relevance Heat
Inflammation 80 99.76 Very High Very High Very High
agonist 4 99.44 Very High Very High Very High
rheumatoid arthritis 5 86.40 High High
cytokine 11 82.56 Quite High
backache 1 80.72 Quite High
Sciatica 1 79.84 Quite High
Potency 2 57.12 Quite High
addiction 4 46.24 Quite Low
halothane 1 42.48 Quite Low
anesthesia 1 41.68 Quite Low
Disease Link Frequency Relevance Heat
INFLAMMATION 93 99.76 Very High Very High Very High
Osteoarthritis 6 99.50 Very High Very High Very High
Prolapse 2 91.32 High High
Sepsis 2 87.12 High High
Rheumatoid Arthritis 5 86.40 High High
Rhinitis 1 85.52 High High
Low Back Pain 1 80.72 Quite High
Nerve Root Compression 1 79.84 Quite High
Intervertebral Disk Displacement 1 77.72 Quite High
Disease 19 62.32 Quite High

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
Only cell-associated (disc cells, hyaline cartilage chondrocytes) sPLA2 and cPLA2 immunoreactivity could be observed.
Regulation (immunoreactivity) of cPLA2 in chondrocytes associated with osteoarthritis
1) Confidence 0.25 Published 1998 Journal Eur Spine J Section Abstract Doc Link 9840472 Disease Relevance 0.59 Pain Relevance 0.16
Ca2+-regulated cytosolic PLA2 (cPLA2)
Regulation (regulated) of cPLA2
2) Confidence 0.25 Published 2008 Journal J Leukoc Biol Section Body Doc Link PMC2567897 Disease Relevance 0.06 Pain Relevance 0.08
The modulation of sPLA2 and/or cPLA2 activity is important in controlling the inflammatory process.
Regulation (modulation) of cPLA2 associated with inflammation
3) Confidence 0.11 Published 2005 Journal Yonsei Medical Journal Section Body Doc Link PMC2562783 Disease Relevance 0.80 Pain Relevance 0.31
The heterotetramer was indicated in the production of prostaglandins through the regulation of cytosolic phospholipase A2 (cPLA2) and arachidonic acid release.
Regulation (regulation) of cytosolic phospholipase A2
4) Confidence 0.07 Published 2007 Journal J. Mol. Endocrinol. Section Abstract Doc Link 17446234 Disease Relevance 0 Pain Relevance 0

General Comments

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