INT78817

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Context Info
Confidence 0.35
First Reported 1998
Last Reported 2002
Negated 0
Speculated 0
Reported most in Abstract
Documents 2
Total Number 2
Disease Relevance 0
Pain Relevance 0.48

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

transport (Scnn1a) plasma membrane (Scnn1a)
Anatomy Link Frequency
neurons 1
Scnn1a (Mus musculus)
Pain Link Frequency Relevance Heat
Endep 8 99.98 Very High Very High Very High
Analgesic 1 98.84 Very High Very High Very High
tricyclic antidepressant 1 97.72 Very High Very High Very High
substance P 1 96.36 Very High Very High Very High
ASIC 1 93.40 High High
Mechanosensation 1 59.20 Quite High
qutenza 1 25.00 Low Low

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Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
We assumed that, having a common protein structure, characterization of the amitriptyline-ENaC interaction could help to elucidate the analgesic mechanism of this tricyclic antidepressant.
ENaC Binding (interaction) of associated with analgesic, tricyclic antidepressant and endep
1) Confidence 0.35 Published 2002 Journal J. Pharm. Pharmacol. Section Abstract Doc Link 12396302 Disease Relevance 0 Pain Relevance 0.40
We conclude that the ENaC complex in the pelvic uroepithelium participates in the activation of renal pelvic mechanosensitive neurons.
ENaC Binding (complex) of in neurons
2) Confidence 0.20 Published 1998 Journal Am. J. Physiol. Section Abstract Doc Link 9843867 Disease Relevance 0 Pain Relevance 0.08

General Comments

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