INT7887

From wiki-pain
Jump to: navigation, search
Context Info
Confidence 0.16
First Reported 1991
Last Reported 1992
Negated 1
Speculated 0
Reported most in Abstract
Documents 2
Total Number 2
Disease Relevance 0
Pain Relevance 1.23

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

extracellular space (Oxt) extracellular region (Oxt) plasma membrane (Oprl1)
response to stress (Oxt) cytoplasm (Oxt) signal transducer activity (Oprl1)
Anatomy Link Frequency
nerve 2
Oprl1 (Rattus norvegicus)
Oxt (Rattus norvegicus)
Pain Link Frequency Relevance Heat
antagonist 13 100.00 Very High Very High Very High
agonist 6 100.00 Very High Very High Very High
Kappa opioid receptor 2 100.00 Very High Very High Very High
MU agonist 5 95.44 Very High Very High Very High
Enkephalin 1 94.56 High High
Dynorphin 2 86.72 High High
narcan 5 81.68 Quite High
opiate 1 79.68 Quite High
opioid receptor 1 75.00 Quite High
Intracerebroventricular 1 62.32 Quite High

|}

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
Two kappa-receptor antagonists, MR 2266 and diprenorphin, alone had no effect on vasopressin and oxytocin secretion from isolated nerve endings depolarized with potassium.
kappa-receptor Neg (no) Regulation (effect) of Localization (secretion) of oxytocin in nerve associated with antagonist
1) Confidence 0.16 Published 1992 Journal Exp Brain Res Section Abstract Doc Link 1358668 Disease Relevance 0 Pain Relevance 0.79
The effects of highly selective agonists and antagonists to the mu-, delta- and kappa-opioid receptor subtypes were studied on the vasopressin and oxytocin release in 24 h water-deprived male rats.
kappa-opioid receptor Regulation (effects) of Localization (release) of oxytocin associated with antagonist, kappa opioid receptor and agonist
2) Confidence 0.08 Published 1991 Journal Eur. J. Pharmacol. Section Abstract Doc Link 1665795 Disease Relevance 0 Pain Relevance 0.44

General Comments

This test has worked.

Personal tools
Namespaces

Variants
Actions
Navigation
Toolbox