INT78941

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Context Info
Confidence 0.45
First Reported 1998
Last Reported 2010
Negated 0
Speculated 0
Reported most in Body
Documents 4
Total Number 4
Disease Relevance 2.46
Pain Relevance 0.23

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

nucleolus (DDX41) RNA binding (DDX41) nucleus (DDX41)
helicase activity (DDX41)
Anatomy Link Frequency
heart 2
DDX41 (Homo sapiens)
Pain Link Frequency Relevance Heat
idiopathic sensory neuropathy 1 96.68 Very High Very High Very High
Neuritis 11 92.24 High High
Multiple sclerosis 14 90.80 High High
depression 8 5.00 Very Low Very Low Very Low
Arthritis 8 5.00 Very Low Very Low Very Low
Demyelination 7 5.00 Very Low Very Low Very Low
Central nervous system 4 5.00 Very Low Very Low Very Low
Sicca syndrome 3 5.00 Very Low Very Low Very Low
Angina 2 5.00 Very Low Very Low Very Low
headache 2 5.00 Very Low Very Low Very Low
Disease Link Frequency Relevance Heat
Heart Rate Under Development 4 100.00 Very High Very High Very High
Neuromyelitis Optica 94 98.92 Very High Very High Very High
Neuropathic Pain 8 98.24 Very High Very High Very High
Disease 16 96.88 Very High Very High Very High
Optic Neuritis 10 92.24 High High
Demyelinating Disease 26 90.80 High High
Neurological Disease 9 90.24 High High
Recurrence 6 77.12 Quite High
Small Cell Lung Carcinoma 1 68.32 Quite High
Small Cell Lung Cancer 3 66.16 Quite High

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
Anti-Hu antibodies (Hu-Abs) were positive in 40 patients with paraneoplastic sensory neuropathy (PSN) and in 1 patient with idiopathic sensory neuropathy in a series of 126 patients who presented with clinical features suggestive of PSN.
Positive_regulation (positive) of Abs associated with idiopathic sensory neuropathy and neuropathic pain
1) Confidence 0.45 Published 1998 Journal Ann. Neurol. Section Abstract Doc Link 9851446 Disease Relevance 0.84 Pain Relevance 0.10
Moderate activity: based on physical activity for sport, recreation or fitness which caused a moderate increase in heart rate or breathing (ABS 2005)
Positive_regulation (increase) of ABS in heart associated with heart rate under development
2) Confidence 0.40 Published 2007 Journal BMC Geriatr Section Body Doc Link PMC1828159 Disease Relevance 0.19 Pain Relevance 0
Vigorous activity: based on physical activity for sport, recreation or fitness which caused a large increase in heart rate or breathing (ABS 2005)
Positive_regulation (increase) of ABS in heart associated with heart rate under development
3) Confidence 0.37 Published 2007 Journal BMC Geriatr Section Body Doc Link PMC1828159 Disease Relevance 0.25 Pain Relevance 0
In comparison to AQP4-IgG, AQP4-IgM Abs are not a reliable biomarker, although they were elevated in definite and high risk NMO patients.
Positive_regulation (elevated) of Abs associated with neuromyelitis optica
4) Confidence 0.15 Published 2010 Journal PLoS ONE Section Body Doc Link PMC2864757 Disease Relevance 1.18 Pain Relevance 0.14

General Comments

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