INT78949

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Context Info
Confidence 0.18
First Reported 1998
Last Reported 2000
Negated 0
Speculated 0
Reported most in Abstract
Documents 3
Total Number 3
Disease Relevance 0.57
Pain Relevance 1.30

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

cytosol (Nisch) endosome (Nisch) plasma membrane (Nisch)
cytoplasm (Nisch)
Anatomy Link Frequency
nucleus 2
Nisch (Mus musculus)
Pain Link Frequency Relevance Heat
antagonist 5 98.26 Very High Very High Very High
Rostral ventrolateral medulla 10 96.52 Very High Very High Very High
medulla 1 88.40 High High
Clonidine 10 83.56 Quite High
Disease Link Frequency Relevance Heat
Pressure Volume 2 Under Development 7 88.72 High High
Stress 1 86.68 High High

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
However, we also found that alpha 2-adrenoceptors are present in this nucleus and appear to be activated as a consequence of imidazoline receptor activation.
Positive_regulation (activation) of imidazoline receptor in nucleus
1) Confidence 0.18 Published 1999 Journal Ann. N. Y. Acad. Sci. Section Abstract Doc Link 10415926 Disease Relevance 0.08 Pain Relevance 0.52
We also found, using microinjection of specific antagonists, that alpha2-adrenoceptors in this nucleus appear to be activated as a consequence of imidazoline receptor activation.
Positive_regulation (activation) of imidazoline receptor in nucleus associated with antagonist
2) Confidence 0.04 Published 1998 Journal J. Auton. Nerv. Syst. Section Abstract Doc Link 9851565 Disease Relevance 0.24 Pain Relevance 0.52
Our results also suggest that alpha2-adrenoceptors are activated as a consequence of imidazoline receptor activation by rilmenidine.
Positive_regulation (activation) of imidazoline receptor
3) Confidence 0.04 Published 2000 Journal Am. J. Hypertens. Section Abstract Doc Link 10921527 Disease Relevance 0.24 Pain Relevance 0.26

General Comments

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