INT78957

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Context Info
Confidence 0.17
First Reported 1998
Last Reported 1998
Negated 0
Speculated 0
Reported most in Abstract
Documents 1
Total Number 1
Disease Relevance 0.49
Pain Relevance 0.72

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

lipid binding (Ptgs2) nuclear envelope (Ptgs2) oxidoreductase activity (Ptgs2)
endoplasmic reticulum (Ptgs2) nucleus (Ptgs2) enzyme binding (Ptgs2)
Ptgs2 (Rattus norvegicus)
Pain Link Frequency Relevance Heat
cINOD 7 99.76 Very High Very High Very High
diclofenac 4 97.64 Very High Very High Very High
COX2 1 25.00 Low Low
Disease Link Frequency Relevance Heat
Apoptosis 5 75.00 Quite High
INFLAMMATION 2 75.00 Quite High
Colon Cancer 1 70.72 Quite High

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
The effect of [3,4-di(4-methoxyphenyl)-5-isoxazolyl] acetic acid (mofezolac), a potent and highly preferential inhibitor of cyclooxygenase-1, and N-[2-(cyclohexyloxy)-4-nitrophenyl]methanesulphonamide (NS-398), a selective inhibitor of cyclooxygenase-2, on DNA fragmentation and cyclooxygenase-2 mRNA expression was weak compared to the effect of indomethacin or sodium diclofenac.
Regulation (effect) of Transcription (expression) of cyclooxygenase-2 associated with diclofenac
1) Confidence 0.17 Published 1998 Journal Eur. J. Pharmacol. Section Abstract Doc Link 9851595 Disease Relevance 0.49 Pain Relevance 0.72

General Comments

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