INT79015

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Context Info
Confidence 0.39
First Reported 1998
Last Reported 2010
Negated 0
Speculated 0
Reported most in Abstract
Documents 3
Total Number 3
Disease Relevance 0.24
Pain Relevance 0.11

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

cytosol (Gstt1) cytoplasm (Gstt1)
Anatomy Link Frequency
liver 1
Gstt1 (Rattus norvegicus)
Pain Link Frequency Relevance Heat
cINOD 4 56.00 Quite High
Chronic pancreatitis 1 5.00 Very Low Very Low Very Low
alcohol 1 5.00 Very Low Very Low Very Low
Disease Link Frequency Relevance Heat
Cancer 2 73.32 Quite High
Gastrointestinal Neoplasms 2 57.44 Quite High
INFLAMMATION 2 55.44 Quite High
Alcoholic Pancreatitis 3 50.00 Quite Low
Pancreatitis 3 44.64 Quite Low

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
In control Wistar rats, gastrointestinal rGSTT1-1 protein levels were highest in the liver and decreased in the order liver > stomach > colon > oesophagus > small intestine.
Negative_regulation (decreased) of rGSTT1-1 in liver
1) Confidence 0.39 Published 1998 Journal Carcinogenesis Section Abstract Doc Link 9855024 Disease Relevance 0.19 Pain Relevance 0.11
Ellagic acid, on the other hand, reduced hepatic rGSTT1-1 protein levels to 53% of the control.
Negative_regulation (reduced) of rGSTT1-1
2) Confidence 0.28 Published 1998 Journal Carcinogenesis Section Abstract Doc Link 9855024 Disease Relevance 0.05 Pain Relevance 0
However, the gene deletion of GSTM1 and GSTT1, and the C-allele of NQO1 cannot be ruled out for association with alcoholism.


Negative_regulation (deletion) of GSTT1
3) Confidence 0.09 Published 2010 Journal Alcohol. Clin. Exp. Res. Section Body Doc Link 18986377 Disease Relevance 0 Pain Relevance 0

General Comments

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