INT79067

Context Info Confidence 0.78 First Reported 1998 Last Reported 2007 Negated 0 Speculated 0 Reported most in Body Documents 2 Total Number 2 Disease Relevance 1.90 Pain Relevance 0.16

Pain Term Frequency Confidence Heat Deep tissue 1 81.44 Pain 2 78.96 cytokine 1 77.72 Paracetamol 1 5.00 alcohol 1 5.00

Disease Term Frequency Confidence Heat Disease 4 98.20 Infection 7 95.44 Streptococcus Infection 11 90.56 Acute Renal Failure 1 88.52 Soft Tissue Infections 2 88.08 Confusion 1 86.84 Pressure Volume 2 Under Development 1 86.40 Streptococcal Infections 5 85.32 Staphylococcus Infection 4 84.32 Pain 2 78.96

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Key:

Protein

Mutation

Event

Anatomy

Negation

Speculation

Pain term

Disease term

Anecdotal evidence suggests that intravenous immunoglobulin may have a place in neutralizing the secreted streptococcal toxins that are thought to mediate features of the disease.

Localization (secreted) of streptococcal toxins associated with disease

1) Confidence 0.78 Published 1998 Journal Postgrad Med Section Abstract Doc Link 9861255 Disease Relevance 1.17 Pain Relevance 0.12

Anecdotal evidence suggests that intravenous immunoglobulin [IVIG] may have a place in neutralising the secreted streptococcal toxins that are thought to mediate features of the disease [24].

Localization (secreted) of streptococcal toxins associated with disease

2) Confidence 0.68 Published 2007 Journal J Med Case Reports Section Body Doc Link PMC2174498 Disease Relevance 0.73 Pain Relevance 0.04

General Comments

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