INT79141

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Context Info
Confidence 0.01
First Reported 1998
Last Reported 2010
Negated 0
Speculated 0
Reported most in Abstract
Documents 3
Total Number 3
Disease Relevance 2.95
Pain Relevance 1.61

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

cytosol (NPEPPS) peptidase activity (NPEPPS) nucleus (NPEPPS)
cytoplasm (NPEPPS)
Anatomy Link Frequency
tendon cells 2
knee 2
NPEPPS (Homo sapiens)
Pain Link Frequency Relevance Heat
cytokine 17 100.00 Very High Very High Very High
metalloproteinase 14 100.00 Very High Very High Very High
cINOD 11 100.00 Very High Very High Very High
Inflammation 19 98.32 Very High Very High Very High
Inflammatory mediators 3 94.36 High High
Pain 17 90.20 High High
Lasting pain 4 82.64 Quite High
rheumatoid arthritis 2 81.88 Quite High
Inflammatory response 3 80.92 Quite High
imagery 9 5.00 Very Low Very Low Very Low
Disease Link Frequency Relevance Heat
INFLAMMATION 27 100.00 Very High Very High Very High
Stress 6 98.92 Very High Very High Very High
Injury 32 98.24 Very High Very High Very High
Adhesions 2 92.28 High High
Pain 18 90.20 High High
Tendinopathy 114 89.92 High High
Pressure And Volume Under Development 4 89.36 High High
Synovitis 2 88.44 High High
Death 2 83.12 Quite High
Rupture 16 82.00 Quite High

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
Recent findings showed that the expression of MMP and tissue inhibitor of metalloproteinase (TIMP) in tendon cells were sensitive to mechanical overload or stress-deprivation [131,154].
Regulation (sensitive) of Gene_expression (expression) of metalloproteinase in tendon cells associated with stress and metalloproteinase
1) Confidence 0.01 Published 2010 Journal Sports Med Arthrosc Rehabil Ther Technol Section Body Doc Link PMC3006368 Disease Relevance 1.64 Pain Relevance 0.43
In vitro effects of non-steroidal anti-inflammatory drugs on cytokine, prostanoid and matrix metalloproteinase production by interface membranes from loose hip or knee endoprostheses.
Regulation (effects) of Gene_expression (production) of metalloproteinase in knee associated with inflammation, metalloproteinase, cinod and cytokine
2) Confidence 0.00 Published 2007 Journal Osteoarthr. Cartil. Section Title Doc Link 17188523 Disease Relevance 0.20 Pain Relevance 0.63
A decrease of cytokine-regulated metalloproteinase expression results in normalization of circulating MMP-1 and MMP-3 levels.
Regulation (regulated) of Gene_expression (expression) of metalloproteinase associated with metalloproteinase and cytokine
3) Confidence 0.00 Published 1998 Journal Z Rheumatol Section Abstract Doc Link 9864833 Disease Relevance 1.12 Pain Relevance 0.55

General Comments

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