INT79229

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Context Info
Confidence 0.09
First Reported 1998
Last Reported 1998
Negated 0
Speculated 0
Reported most in Abstract
Documents 1
Total Number 1
Disease Relevance 0.37
Pain Relevance 0.14

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

extracellular space (Icam1) cell adhesion (Icam1) plasma membrane (Icam1)
Anatomy Link Frequency
polymorphonuclear leukocytes 1
Icam1 (Mus musculus)
Ltbr (Mus musculus)
Pain Link Frequency Relevance Heat
cINOD 3 75.00 Quite High
Disease Link Frequency Relevance Heat
Injury 2 90.28 High High
Necrosis 1 81.40 Quite High
Cancer 1 81.04 Quite High
Adhesions 2 68.24 Quite High

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
We conclude from these studies that indomethacin activates NFKB (possibly via TNF synthesis) in gastric microvascular endothelial cells, thereby enhancing surface expression of ICAM-1 which binds the CD18 on polymorphonuclear leukocytes (PMNs).
ICAM-1 Binding (binds) of CD18 in polymorphonuclear leukocytes
1) Confidence 0.09 Published 1998 Journal J. Clin. Gastroenterol. Section Abstract Doc Link 9872503 Disease Relevance 0.37 Pain Relevance 0.14

General Comments

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