INT7927

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Context Info
Confidence 0.26
First Reported 1984
Last Reported 1992
Negated 0
Speculated 0
Reported most in Abstract
Documents 2
Total Number 2
Disease Relevance 0.66
Pain Relevance 1.09

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

extracellular region (Penk, Trh) plasma membrane (Trh) nucleus (Trh)
cytoplasm (Trh)
Penk (Rattus norvegicus)
Trh (Rattus norvegicus)
Pain Link Frequency Relevance Heat
Enkephalin 7 100.00 Very High Very High Very High
Dynorphin 5 100.00 Very High Very High Very High
Somatostatin 1 99.96 Very High Very High Very High
amygdala 2 85.76 High High
Neuropeptide 2 84.56 Quite High
Nucleus accumbens 1 80.56 Quite High
Central nervous system 3 74.24 Quite High
Disease Link Frequency Relevance Heat
Convulsion 10 96.52 Very High Very High Very High
Epilepsy 1 25.00 Low Low

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
Changes in expression developed as kindling progressed, with long-lasting changes in ENK and transient changes in DYN and TRH.
ENK Regulation (changes) of TRH associated with dynorphin and enkephalin
1) Confidence 0.26 Published 1992 Journal Brain Res. Mol. Brain Res. Section Abstract Doc Link 1359374 Disease Relevance 0.66 Pain Relevance 0.80
Neither Luteinizing hormone-releasing hormone (LHRH), neurotensin, somatostatin, D-Ala-Met-enkephalin nor VIP showed any significant affinity for TRH binding sites.
D-Ala-Met-enkephalin Regulation (affinity) of TRH associated with somatostatin and enkephalin
2) Confidence 0.09 Published 1984 Journal Neuroendocrinology Section Abstract Doc Link 6087185 Disease Relevance 0 Pain Relevance 0.29

General Comments

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