INT79311

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Context Info
Confidence 0.49
First Reported 1998
Last Reported 1998
Negated 0
Speculated 0
Reported most in Abstract
Documents 1
Total Number 2
Disease Relevance 0.34
Pain Relevance 0.47

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isomerase activity (PDIA3) protein folding (PDIA3) signal transduction (PDIA3)
endoplasmic reticulum (PDIA3)
PDIA3 (Homo sapiens)
Pain Link Frequency Relevance Heat
agonist 2 100.00 Very High Very High Very High
opioid receptor 4 99.02 Very High Very High Very High
Opioid 2 94.24 High High
Disease Link Frequency Relevance Heat
Bordatella Infection 4 93.96 High High

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
In COS-7 cells coexpressing one of the three opioid receptors (mu, delta, and kappa) and a Galpha(q) chimera, agonist-induced stimulation of phosphoinositide-specific phospholipase C (PI-PLC) was largely insensitive to PTX treatment.
Positive_regulation (agonist-induced) of Positive_regulation (stimulation) of PI-PLC associated with agonist and opioid receptor
1) Confidence 0.49 Published 1998 Journal FEBS Lett. Section Abstract Doc Link 9877167 Disease Relevance 0.17 Pain Relevance 0.23
In COS-7 cells coexpressing one of the three opioid receptors (mu, delta, and kappa) and a Galpha(q) chimera, agonist-induced stimulation of phosphoinositide-specific phospholipase C (PI-PLC) was largely insensitive to PTX treatment.
Positive_regulation (insensitive) of Positive_regulation (stimulation) of PI-PLC associated with agonist and opioid receptor
2) Confidence 0.49 Published 1998 Journal FEBS Lett. Section Abstract Doc Link 9877167 Disease Relevance 0.17 Pain Relevance 0.24

General Comments

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