INT79361

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Context Info
Confidence 0.51
First Reported 1998
Last Reported 2010
Negated 0
Speculated 0
Reported most in Body
Documents 5
Total Number 5
Disease Relevance 3.79
Pain Relevance 1.40

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

methyltransferase activity (Prdm6) nucleus (Prdm6) intracellular (Prdm6)
Anatomy Link Frequency
tubes 1
Prdm6 (Mus musculus)
Pain Link Frequency Relevance Heat
Angina 8 100.00 Very High Very High Very High
addiction 27 97.92 Very High Very High Very High
alcohol 21 97.08 Very High Very High Very High
cocaine 5 95.64 Very High Very High Very High
cannabis 3 95.16 Very High Very High Very High
aspirin 6 92.12 High High
withdrawal 6 88.80 High High
Nicotine 2 86.64 High High
adenocard 2 79.16 Quite High
antagonist 4 73.12 Quite High
Disease Link Frequency Relevance Heat
Myocardial Infarction 13 100.00 Very High Very High Very High
Cv General 3 Under Development 8 100.00 Very High Very High Very High
Death 8 98.00 Very High Very High Very High
Alcohol Addiction 7 97.32 Very High Very High Very High
Cv Unclassified Under Development 2 97.16 Very High Very High Very High
Cocaine Dependence 2 96.08 Very High Very High Very High
Diabetes Mellitus 151 94.88 High High
Severe Combined Immunodeficiency 15 93.68 High High
Drug Dependence 34 90.08 High High
Impulse Control Disorders 1 84.40 Quite High

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
In PRISM-PLUS, a study involving 1915 patients with unstable angina/non-Q-wave MI, administration of intravenous tirofiban (0.4 microgram/kg/min loading dose for 30 minutes followed by a 0.10 microgram/kg/min infusion) with heparin for at least 48 (mean 71.3) hours reduced the 7-day risk of the composite end-point of MI, death and refractory ischaemia by 32% compared with heparin alone.
Negative_regulation (reduced) of PRISM-PLUS associated with angina, cv unclassified under development, death and myocardial infarction
1) Confidence 0.51 Published 1998 Journal Drugs Section Abstract Doc Link 9878994 Disease Relevance 1.01 Pain Relevance 0.32
Total cDNA synthesis was performed using ABI PRISM cDNA archive kit in 0.2 ml microfuge tubes.
Negative_regulation (using) of PRISM in tubes
2) Confidence 0.41 Published 2010 Journal J Biomed Sci Section Body Doc Link PMC2890658 Disease Relevance 0 Pain Relevance 0
In PRISM-PLUS, a study involving 1915 patients with unstable angina/non-Q-wave MI, administration of intravenous tirofiban (0.4 microgram/kg/min loading dose for 30 minutes followed by a 0.10 microgram/kg/min infusion) with heparin for at least 48 (mean 71.3) hours reduced the 7-day risk of the composite end-point of MI, death and refractory ischaemia by 32% compared with heparin alone.
Negative_regulation (reduced) of PRISM-PLUS associated with angina, cv unclassified under development, death and myocardial infarction
3) Confidence 0.37 Published 1998 Journal Drugs Section Abstract Doc Link 9878994 Disease Relevance 1.01 Pain Relevance 0.32
Correlations between PRISM-RII (IPM and SIS) and other variables are presented in Table 2.
Negative_regulation (presented) of PRISM-RII
4) Confidence 0.32 Published 2008 Journal Health Qual Life Outcomes Section Body Doc Link PMC2627820 Disease Relevance 0.80 Pain Relevance 0
The English version of the PRISM can be downloaded, together with training information (www.columbia.edu/~dsh2/prism).
Negative_regulation (downloaded) of PRISM
5) Confidence 0.14 Published 2007 Journal Addiction Science & Clinical Practice Section Body Doc Link PMC2797097 Disease Relevance 0.96 Pain Relevance 0.76

General Comments

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