INT79428

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Context Info
Confidence 0.11
First Reported 1998
Last Reported 2010
Negated 2
Speculated 0
Reported most in Body
Documents 3
Total Number 4
Disease Relevance 0.87
Pain Relevance 0.69

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

mitochondrion (Snd1) nucleus (Snd1) biological_process (Snd1)
cytoplasm (Snd1) nuclease activity (Snd1)
Anatomy Link Frequency
hypothalamus 1
liver 1
Snd1 (Mus musculus)
Pain Link Frequency Relevance Heat
bradykinin 4 98.08 Very High Very High Very High
Neuropeptide 8 97.84 Very High Very High Very High
antagonist 10 97.78 Very High Very High Very High
c fibre 1 97.32 Very High Very High Very High
qutenza 3 95.00 High High
dexamethasone 1 68.68 Quite High
agonist 20 18.80 Low Low
Intracerebroventricular 26 5.00 Very Low Very Low Very Low
bDMF 12 5.00 Very Low Very Low Very Low
Central nervous system 6 5.00 Very Low Very Low Very Low
Disease Link Frequency Relevance Heat
Peritonitis 1 96.08 Very High Very High Very High
Tics 1 93.36 High High
Pressure And Volume Under Development 8 92.32 High High
Weight Loss 2 81.80 Quite High
Hypoglycemia 6 70.24 Quite High
Diabetes Mellitus 5 25.00 Low Low
Targeted Disruption 2 16.32 Low Low
Obesity 12 11.28 Low Low
Body Weight 12 5.00 Very Low Very Low Very Low
Repression 4 5.00 Very Low Very Low Very Low

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
The tachykinin NK(2) receptor antagonist (S)-N-methyl-N[4-(4-acetylamino-4-phenyl piperidino)-2-(3, 4-dichlorophenyl)butyl]-benzamide (SR48968) had no effect on the staphylococcal enterotoxin B-induced responses.
Neg (no) Regulation (effect) of staphylococcal enterotoxin B associated with antagonist
1) Confidence 0.11 Published 2000 Journal Eur. J. Pharmacol. Section Abstract Doc Link 10884525 Disease Relevance 0.47 Pain Relevance 0.33
More recently, a protein with a crucial function in the maintenance of glucose homeostasis, the cyclic AMP-response element binding protein (CREB) regulated protein co-activator 2 (CRTC2) has been described as displaying a differential regulation by the nutritional status in liver and hypothalamus [44].
Regulation (regulation) of co-activator 2 in liver
2) Confidence 0.01 Published 2010 Journal PLoS ONE Section Body Doc Link PMC2956692 Disease Relevance 0.15 Pain Relevance 0
In contrast, indomethacin (5 mg/kg) had no effect on staphylococcal enterotoxin type A-induced chemotaxis.
Neg (no) Regulation (effect) of staphylococcal enterotoxin
3) Confidence 0.01 Published 1998 Journal Eur. J. Pharmacol. Section Abstract Doc Link 9881589 Disease Relevance 0.10 Pain Relevance 0.36
More recently, a protein with a crucial function in the maintenance of glucose homeostasis, the cyclic AMP-response element binding protein (CREB) regulated protein co-activator 2 (CRTC2) has been described as displaying a differential regulation by the nutritional status in liver and hypothalamus [44].
Regulation (regulation) of co-activator 2 in hypothalamus
4) Confidence 0.00 Published 2010 Journal PLoS ONE Section Body Doc Link PMC2956692 Disease Relevance 0.15 Pain Relevance 0

General Comments

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