INT79447

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Context Info
Confidence 0.19
First Reported 1999
Last Reported 1999
Negated 0
Speculated 0
Reported most in Abstract
Documents 1
Total Number 2
Disease Relevance 0
Pain Relevance 0

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

cytosol (IRF6, PDE4B) nucleus (IRF6, PDE4B) cytoplasm (IRF6, PDE4B)
signal transduction (PDE4B) DNA binding (IRF6)
Anatomy Link Frequency
monocytes 2
IRF6 (Homo sapiens)
PDE4B (Homo sapiens)
Pain Link Frequency Relevance Heat
cINOD 2 43.76 Quite Low
Disease Link Frequency Relevance Heat
INFLAMMATION 2 5.00 Very Low Very Low Very Low

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
We also demonstrate that LPS induction of PDE4B mRNA expression was inhibited strongly by interleukin (IL)-10.
LPS Positive_regulation (induction) of Transcription (expression) of PDE4B
1) Confidence 0.19 Published 1999 Journal Mol. Pharmacol. Section Abstract Doc Link 9882697 Disease Relevance 0 Pain Relevance 0
In the present study, we demonstrate, for the first time, that lipopolysaccharide (LPS) significantly and selectively stimulated PDE4B mRNA production in human monocytes.
LPS Positive_regulation (stimulated) of Transcription (production) of PDE4B in monocytes
2) Confidence 0.19 Published 1999 Journal Mol. Pharmacol. Section Abstract Doc Link 9882697 Disease Relevance 0 Pain Relevance 0

General Comments

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