INT79487

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Context Info
Confidence 0.07
First Reported 1999
Last Reported 1999
Negated 0
Speculated 0
Reported most in Abstract
Documents 1
Total Number 1
Disease Relevance 0.65
Pain Relevance 0.04

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

cytosol (Pde4b) signal transduction (Pde4b) nucleus (Pde4b)
cytoplasm (Pde4b)
Pde4b (Rattus norvegicus)
Pain Link Frequency Relevance Heat
ischemia 1 85.40 High High
anesthesia 1 25.00 Low Low
Disease Link Frequency Relevance Heat
Myocardial Infarction 2 88.44 High High
Reperfusion Injury 2 86.16 High High
Coronary Artery Disease 1 85.40 High High
Necrosis 2 83.48 Quite High
Cancer 2 83.12 Quite High
Myocardial Reperfusion Injury 1 75.00 Quite High

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
Three groups of rats were studied: vehicle controls (n=6); positive controls for infarct size reduction (ischemic preconditioning; n=6); and a group treated with the selective inhibitor of PDE-IV and TNF-alpha production, rolipram (1 mg/kg i.v. 10-min prereperfusion + 1 microg/kg per minute through 1-hr reperfusion, n=6). 4.
Negative_regulation (inhibitor) of Gene_expression (production) of PDE-IV
1) Confidence 0.07 Published 1999 Journal Gen. Pharmacol. Section Abstract Doc Link 9888252 Disease Relevance 0.65 Pain Relevance 0.04

General Comments

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