INT79532

Context Info Confidence 0.00 First Reported 1999 Last Reported 1999 Negated 1 Speculated 0 Reported most in Abstract Documents 1 Total Number 1 Disease Relevance 0 Pain Relevance 0.76

extracellular space (Crh) extracellular region (Crh) transferase activity, transferring glycosyl groups (Ugt1a10) molecular_function (Ugt1a10) cellular_component (Ugt1a10) biological_process (Ugt1a10)

Crh (Rattus norvegicus) Ugt1a10 (Mus musculus)

Pain Link Frequency Relevance Heat antagonist 2 100.00 Dynorphin 10 99.98 dexamethasone 1 91.60 nMDA receptor 2 86.72 MU agonist 1 75.44 narcan 1 71.64

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Sentences Mentioned In

Key:

Protein

Mutation

Event

Anatomy

Negation

Speculation

Pain term

Disease term

The response to both dynorphin A1-13 and NMDA was significantly attenuated by pretreatment with the noncompetitive NMDA antagonist, MK-801, but was not affected by antagonists of corticotropin-releasing hormone and arginine vasopressin.

corticotropin-releasing hormone Neg (not) Regulation (affected) of A1-13 associated with dynorphin and antagonist

1) Confidence 0.00 Published 1999 Journal Neuroendocrinology Section Abstract Doc Link 9892848 Disease Relevance 0 Pain Relevance 0.76

General Comments

This test has worked.