INT79577

From wiki-pain
Jump to: navigation, search
Context Info
Confidence 0.12
First Reported 1999
Last Reported 1999
Negated 0
Speculated 0
Reported most in Abstract
Documents 1
Total Number 2
Disease Relevance 0.35
Pain Relevance 0.40

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

extracellular region (APP, PENK) Golgi apparatus (APP) extracellular matrix organization (APP)
DNA binding (APP) cytoplasm (APP) cytosol (APP)
APP (Homo sapiens)
PENK (Homo sapiens)
Pain Link Frequency Relevance Heat
Neurotransmitter 2 93.24 High High
Enkephalin 4 69.84 Quite High
medulla 2 66.32 Quite High
Disease Link Frequency Relevance Heat
Alzheimer's Dementia 4 100.00 Very High Very High Very High
Disease 2 5.00 Very Low Very Low Very Low
Aging 2 5.00 Very Low Very Low Very Low

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
This study demonstrates that "protease nexin 2 (PN2)," the secreted form of the kunitz protease inhibitor (KPI) of the amyloid precursor protein (APP), potently inhibited the proenkephalin processing enzyme known as prohormone thiol protease (PTP), with a Ki,app of 400 nM.
PN2 Negative_regulation (inhibited) of proenkephalin associated with alzheimer's dementia
1) Confidence 0.12 Published 1999 Journal J. Biol. Chem. Section Abstract Doc Link 9915856 Disease Relevance 0.17 Pain Relevance 0.20
This study demonstrates that "protease nexin 2 (PN2)," the secreted form of the kunitz protease inhibitor (KPI) of the amyloid precursor protein (APP), potently inhibited the proenkephalin processing enzyme known as prohormone thiol protease (PTP), with a Ki,app of 400 nM.
protease nexin 2 Negative_regulation (inhibited) of proenkephalin associated with alzheimer's dementia
2) Confidence 0.11 Published 1999 Journal J. Biol. Chem. Section Abstract Doc Link 9915856 Disease Relevance 0.17 Pain Relevance 0.20

General Comments

This test has worked.

Personal tools
Namespaces

Variants
Actions
Navigation
Toolbox