INT79622

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Context Info
Confidence 0.14
First Reported 1999
Last Reported 2004
Negated 0
Speculated 0
Reported most in Abstract
Documents 2
Total Number 2
Disease Relevance 0.43
Pain Relevance 1.83

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

nucleus (TP53INP2)
Anatomy Link Frequency
plasma 2
TP53INP2 (Homo sapiens)
Pain Link Frequency Relevance Heat
Dextromethorphan 15 98.60 Very High Very High Very High
qutenza 1 97.00 Very High Very High Very High
Hyperalgesia 2 95.08 Very High Very High Very High
Enkephalin 8 94.04 High High
Pain threshold 1 89.92 High High
Antinociceptive 4 87.52 High High
Pain 1 86.08 High High
Delta opioid receptors 1 75.00 Quite High
Opioid 2 72.32 Quite High
agonist 1 68.48 Quite High
Disease Link Frequency Relevance Heat
Hyperalgesia 2 95.08 Very High Very High Very High
Nociception 1 90.76 High High
Pain 2 89.92 High High

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
Pretreatment of EM by Qd suppressed DOR formation and increased the plasma level of DEM to the levels of poor metabolizers.
Negative_regulation (suppressed) of DOR Binding (formation) of in plasma associated with dextromethorphan
1) Confidence 0.14 Published 1999 Journal J. Pharmacol. Exp. Ther. Section Abstract Doc Link 9918565 Disease Relevance 0.43 Pain Relevance 1.13
Finally, by preventing hDOR internalization with 0.5 M sucrose, we demonstrated that hDOR internalization contributes partially to desensitization.
Negative_regulation (preventing) of hDOR Binding (internalization) of
2) Confidence 0.02 Published 2004 Journal J. Pharmacol. Exp. Ther. Section Abstract Doc Link 15102931 Disease Relevance 0 Pain Relevance 0.70

General Comments

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