INT79719

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Context Info
Confidence 0.43
First Reported 1999
Last Reported 2010
Negated 0
Speculated 0
Reported most in Body
Documents 6
Total Number 6
Disease Relevance 2.94
Pain Relevance 0.21

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

signal transduction (VAPA) small molecule metabolic process (VAPA) cell death (VAPA)
endoplasmic reticulum (VAPA) structural molecule activity (VAPA) plasma membrane (VAPA)
Anatomy Link Frequency
tubes 1
digestive tract 1
head 1
VAPA (Homo sapiens)
Pain Link Frequency Relevance Heat
Versed 1 77.48 Quite High
analgesia 12 75.08 Quite High
anesthesia 1 74.64 Quite High
tolerance 6 51.84 Quite High
Spinal cord 4 31.36 Quite Low
cva 12 5.00 Very Low Very Low Very Low
Inflammation 12 5.00 Very Low Very Low Very Low
dexamethasone 8 5.00 Very Low Very Low Very Low
agonist 8 5.00 Very Low Very Low Very Low
Pain 7 5.00 Very Low Very Low Very Low
Disease Link Frequency Relevance Heat
Pneumonia 196 100.00 Very High Very High Very High
Infection 70 91.36 High High
Paralysis 1 75.68 Quite High
Gastroesophageal Reflux Disease 3 69.32 Quite High
Lower Respiratory Tract Infection 20 63.44 Quite High
Burns 7 61.76 Quite High
Critical Illness 83 58.68 Quite High
Ulcers 7 57.64 Quite High
Stress 6 57.40 Quite High
Sepsis 184 50.00 Quite Low

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
Under these circumstances, 17 of 18 animals and 4 of 9 animals developed VAP in the control and the ATB groups, respectively.
Negative_regulation (developed) of VAP associated with pneumonia
1) Confidence 0.43 Published 1999 Journal Chest Section Abstract Doc Link 9925085 Disease Relevance 0.70 Pain Relevance 0.19
Selective decontamination of the oropharynx, and gastric and subglottic area, or selective digestive tract decontamination (SDD) with several different regimens have been proposed as a method for decreasing VAP.
Negative_regulation (decreasing) of VAP in digestive tract associated with pneumonia
2) Confidence 0.06 Published 2008 Journal Crit Care Section Body Doc Link PMC2447567 Disease Relevance 0.53 Pain Relevance 0
Despite the failure of closed endotracheal suctioning systems to reduce VAP or mortality, these devices may be preferable because of their efficiency and smaller number of suction-induced complications [65] and cost-effectiveness among patients requiring more than 4 days of mechanical ventilation [66].
Negative_regulation (reduce) of VAP associated with pneumonia
3) Confidence 0.04 Published 2008 Journal Crit Care Section Body Doc Link PMC2447567 Disease Relevance 0.33 Pain Relevance 0
A single study has reported that in-line suction systems are associated with a reduction in the incidence of VAP [61], but most studies and a recent meta-analysis find no beneficial effect on nosocomial pneumonia [59,62-64].
Negative_regulation (reduction) of VAP associated with pneumonia
4) Confidence 0.04 Published 2008 Journal Crit Care Section Body Doc Link PMC2447567 Disease Relevance 0.34 Pain Relevance 0
A recent meta-analysis reported that these endotracheal tubes reduce early-onset VAP in patients expected to require more than 72 hours of mechanical ventilation.
Negative_regulation (reduce) of VAP in tubes associated with pneumonia
5) Confidence 0.04 Published 2008 Journal Crit Care Section Body Doc Link PMC2447567 Disease Relevance 0.48 Pain Relevance 0
In comparison to the supine position with a 10° head of bed elevation [120], the 30° elevation did not result in a reduction of VAP incidence.


Negative_regulation (reduction) of VAP in head associated with pneumonia
6) Confidence 0.02 Published 2010 Journal GMS German Medical Science Section Body Doc Link PMC2899863 Disease Relevance 0.56 Pain Relevance 0.03

General Comments

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