INT79747

Context Info Confidence 0.35 First Reported 1999 Last Reported 1999 Negated 0 Speculated 0 Reported most in Abstract Documents 1 Total Number 1 Disease Relevance 0 Pain Relevance 0.60

cell differentiation (Ntrk1) endosome (Ntrk1) aging (Ntrk1) extracellular region (Ntf3) plasma membrane (Ntrk1) cytoplasmic membrane-bounded vesicle (Ntf3)

Anatomy Link Frequency neurons 2 Ntf3 (Rattus norvegicus) Ntrk1 (Rattus norvegicus)

Pain Link Frequency Relevance Heat Somatostatin 9 95.92 Glutamate 1 83.44 Neurotransmitter 1 82.80 antagonist 1 80.96 Glutamate receptor 1 80.48 tetrodotoxin 1 79.48 Nerve growth factor 1 64.92 Neuropeptide 1 49.36 Central nervous system 1 40.04

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Sentences Mentioned In

Key:

Protein

Mutation

Event

Anatomy

Negation

Speculation

Pain term

Disease term

Our results show that, in rat hypothalamic cultures, brain-derived neurotrophic factor, and NT-3 have a potent stimulatory effect on peptide synthesis in somatostatinergic neurons, likely through direct activation of TrkB and TrkC receptors.

NT-3 Regulation (effect) of Positive_regulation (activation) of Trk in neurons

1) Confidence 0.35 Published 1999 Journal Endocrinology Section Abstract Doc Link 9927323 Disease Relevance 0 Pain Relevance 0.60

General Comments

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