INT80118

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Context Info
Confidence 0.68
First Reported 1998
Last Reported 2001
Negated 0
Speculated 0
Reported most in Abstract
Documents 2
Total Number 5
Disease Relevance 4.14
Pain Relevance 0.77

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

extracellular space (NPPC) extracellular region (NPPC)
Anatomy Link Frequency
endothelium 2
myocardium 1
plasma 1
brain 1
NPPC (Homo sapiens)
Pain Link Frequency Relevance Heat
cva 72 93.52 High High
midbrain 4 91.84 High High
Thalamus 4 90.72 High High
anesthesia 9 74.80 Quite High
Disease Link Frequency Relevance Heat
Natriuresis 32 100.00 Very High Very High Very High
Increased Venous Pressure Under Development 76 98.32 Very High Very High Very High
Cerebral Aneurysm 8 96.76 Very High Very High Very High
Cv General 4 Under Development 72 93.52 High High
Muscular Spasm 24 73.68 Quite High
Disease 4 62.12 Quite High
Aneurism 8 5.00 Very Low Very Low Very Low
Renal Disease 4 5.00 Very Low Very Low Very Low
Rupture 4 5.00 Very Low Very Low Very Low
Myocardial Infarction 4 5.00 Very Low Very Low Very Low

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
In man CNP is highly expressed in endothelial cells, distinct brain areas and kidney.
Gene_expression (expressed) of CNP in brain
1) Confidence 0.68 Published 1998 Journal J Perinat Med Section Abstract Doc Link 10027136 Disease Relevance 0.26 Pain Relevance 0.07
In the present study, plasma CNP levels did not change during the monitoring period; this was in agreement with the report of Eelco et al [20] who showed that plasma ANP and BNP levels increased after SAH, whereas plasma CNP and endothelium CNP were independent of ANP and BNP and did not change very much.
Gene_expression (levels) of CNP in plasma associated with cva
2) Confidence 0.56 Published 2001 Journal Crit Care Section Body Doc Link PMC29055 Disease Relevance 0.94 Pain Relevance 0.23
C-type natriuretic peptide (CNP) is present in the brain as a cerebral vasodilator; it is also an endothelium-derived relaxing factor produced via cGMP.
Gene_expression (present) of C-type natriuretic peptide in endothelium associated with natriuresis
3) Confidence 0.50 Published 2001 Journal Crit Care Section Abstract Doc Link PMC29055 Disease Relevance 1.15 Pain Relevance 0.20
ANP and BNP are synthesized predominantly in the myocardium, whereas CNP is synthesized in the vascular endothelium.
Gene_expression (synthesized) of CNP in myocardium
4) Confidence 0.50 Published 2001 Journal Crit Care Section Body Doc Link PMC29055 Disease Relevance 0.66 Pain Relevance 0.06
C-type natriuretic peptide (CNP) is present in the brain as a cerebral vasodilator; it is also an endothelium-derived relaxing factor produced via cGMP.
Gene_expression (present) of CNP in endothelium associated with natriuresis
5) Confidence 0.50 Published 2001 Journal Crit Care Section Abstract Doc Link PMC29055 Disease Relevance 1.14 Pain Relevance 0.20

General Comments

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