INT80187

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Context Info
Confidence 0.58
First Reported 1998
Last Reported 2008
Negated 0
Speculated 0
Reported most in Body
Documents 3
Total Number 4
Disease Relevance 2.45
Pain Relevance 0.09

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

Anatomy Link Frequency
body 1
Hd (Rattus norvegicus)
Pain Link Frequency Relevance Heat
Paracetamol 1 93.56 High High
dexamethasone 14 50.00 Quite Low
Central nervous system 6 5.00 Very Low Very Low Very Low
tolerance 4 5.00 Very Low Very Low Very Low
Inflammation 2 5.00 Very Low Very Low Very Low
Pain 2 5.00 Very Low Very Low Very Low
corticosteroid 1 5.00 Very Low Very Low Very Low
iatrogenic 1 5.00 Very Low Very Low Very Low
anesthesia 1 5.00 Very Low Very Low Very Low
Neuropeptide 1 5.00 Very Low Very Low Very Low
Disease Link Frequency Relevance Heat
Fistula 2 99.24 Very High Very High Very High
Body Weight 8 99.00 Very High Very High Very High
Renal Failure 216 98.62 Very High Very High Very High
Poisoning 1 98.56 Very High Very High Very High
Hepatotoxicity 1 95.64 Very High Very High Very High
Chronic Renal Failure 12 72.92 Quite High
Infection 2 62.92 Quite High
Thrombosis 2 62.32 Quite High
Hyperlipidemia 28 59.04 Quite High
Hyperinsulinism 3 58.40 Quite High

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
Since the protective effect of HD-03 was observed in all three types of intoxication, which are different in their primary mechanism of inducing hepatotoxicity, a protective mode of action of HD-03, not specific to the hepatotoxin, is suggested.
Negative_regulation (effect) of HD-03 associated with hepatotoxicity and poisoning
1) Confidence 0.58 Published 1998 Journal J Ethnopharmacol Section Abstract Doc Link 10030721 Disease Relevance 0.19 Pain Relevance 0.09
The food intake was reduced in the HD, HF-LD and HF rats, but body weight was not affected.
Negative_regulation (reduced) of HD in body associated with body weight
2) Confidence 0.17 Published 2008 Journal Int Arch Med Section Body Doc Link PMC2414485 Disease Relevance 0.60 Pain Relevance 0
In 2005, there were over 97 000 incident HD patients and ?
Negative_regulation (were) of HD
3) Confidence 0.09 Published 2008 Journal Nephrology Dialysis Transplantation Section Body Doc Link PMC2441769 Disease Relevance 0.80 Pain Relevance 0
A peritoneal catheter must be inserted for PD and a vascular access, fistula, graft or temporary catheter must be established for HD.
Negative_regulation (established) of HD associated with fistula and renal failure
4) Confidence 0.09 Published 2008 Journal Nephrology Dialysis Transplantation Section Body Doc Link PMC2441769 Disease Relevance 0.86 Pain Relevance 0

General Comments

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