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Context Info
Confidence 0.48
First Reported 1999
Last Reported 2005
Negated 0
Speculated 0
Reported most in Abstract
Documents 2
Total Number 2
Disease Relevance 0.53
Pain Relevance 0.95

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

signal transduction (Npy2r) plasma membrane (Npy2r) signal transducer activity (Npy2r)
Anatomy Link Frequency
sensory neurons 1
neurons 1
Npy2r (Mus musculus)
Pain Link Frequency Relevance Heat
Neuropeptide 9 98.96 Very High Very High Very High
Root ganglion neuron 3 96.52 Very High Very High Very High
Dorsal horn 2 94.72 High High
dorsal rhizotomy 1 86.48 High High
Pain 1 83.52 Quite High
agonist 2 82.24 Quite High
Spinal cord 2 80.00 Quite High
Calcitonin gene-related peptide 1 76.48 Quite High
Neuropathic pain 1 70.24 Quite High
Sciatic nerve 1 67.60 Quite High
Disease Link Frequency Relevance Heat
Targeted Disruption 1 98.28 Very High Very High Very High
Nociception 1 97.32 Very High Very High Very High
Ganglion Cysts 3 96.20 Very High Very High Very High
Nervous System Injury 1 75.00 Quite High
Pain 1 5.00 Very Low Very Low Very Low
Neuropathic Pain 1 5.00 Very Low Very Low Very Low
Injury 1 5.00 Very Low Very Low Very Low

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
These results demonstrate that the NPY Y2R is associated mainly with both peptidergic and nonpeptidergic small, presumably nociceptive, neurons projecting to the superficial layers of the dorsal horn.
NPY Y2R Binding (associated) of in neurons associated with nociception and dorsal horn
1) Confidence 0.48 Published 2005 Journal J. Comp. Neurol. Section Abstract Doc Link 16025447 Disease Relevance 0.20 Pain Relevance 0.39
It is concluded that neuropeptide Y increases the excitability of sensory neurons by interacting with a Y2-receptor and thereby decreasing N-type Ca2+ channel current and Ca2+-sensitive K+-conductance(s).
Y2-receptor Binding (interacting) of in sensory neurons associated with neuropeptide
2) Confidence 0.12 Published 1999 Journal Neuroscience Section Abstract Doc Link 10051216 Disease Relevance 0.34 Pain Relevance 0.55

General Comments

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