INT80597

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Context Info
Confidence 0.37
First Reported 1999
Last Reported 2010
Negated 0
Speculated 0
Reported most in Abstract
Documents 4
Total Number 5
Disease Relevance 2.54
Pain Relevance 1.01

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

Anatomy Link Frequency
muscle 1
Ptcra (Mus musculus)
Pain Link Frequency Relevance Heat
imagery 6 98.56 Very High Very High Very High
Pain 3 84.88 Quite High
substance P 2 80.40 Quite High
Enkephalin 8 79.76 Quite High
Neuropeptide 2 76.16 Quite High
Patellofemoral syndrome 6 75.00 Quite High
Disease Link Frequency Relevance Heat
Vascular Dementia 2 96.64 Very High Very High Very High
Neurological Disease 8 95.40 Very High Very High Very High
Frontotemporal Dementia 2 94.80 High High
Parkinson's Disease 2 93.44 High High
Dementia 10 92.76 High High
Disease 2 92.08 High High
Pain 3 84.88 Quite High
Patellofemoral Pain Syndrome 6 75.00 Quite High

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
The most frequently observed was tilt and lateralisation, with elevated CA and decreased PTA.
Negative_regulation (decreased) of PTA
1) Confidence 0.37 Published 1999 Journal Arch Orthop Trauma Surg Section Abstract Doc Link 10076944 Disease Relevance 0.23 Pain Relevance 0.26
At 30 degrees of flexion, muscle contraction increased CA and decreased PTA.
Negative_regulation (decreased) of PTA in muscle
2) Confidence 0.37 Published 1999 Journal Arch Orthop Trauma Surg Section Abstract Doc Link 10076944 Disease Relevance 0.13 Pain Relevance 0.22
This decrease of the PTA was statistically significant in extension (P < 0.05) and in 10 degrees of flexion (P < 0.05).
Negative_regulation (decrease) of PTA
3) Confidence 0.37 Published 1999 Journal Arch Orthop Trauma Surg Section Abstract Doc Link 10076944 Disease Relevance 0.21 Pain Relevance 0.28
Median concentrations of NT-PTA were decreased in all patient groups compared to NHC showing significant differences between patients with NHC and AN (p<0.001), OND and AN (p<0.001), FTD and AN (p<0.01) and pAD and AN (p<0.05).
Negative_regulation (decreased) of NT-PTA associated with neurological disease
4) Confidence 0.01 Published 2010 Journal J. Neuroimmunol. Section Abstract Doc Link 20207019 Disease Relevance 1.07 Pain Relevance 0.12
A maximum difference of both proneuropeptide fragments was found between NHC subjects and patients with AN, with a more than 2fold decrease in median NT-PTA and a 1.5fold decrease in median MR-PENK A levels.
Negative_regulation (decrease) of NT-PTA
5) Confidence 0.01 Published 2010 Journal J. Neuroimmunol. Section Abstract Doc Link 20207019 Disease Relevance 0.90 Pain Relevance 0.13

General Comments

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