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Context Info
Confidence 0.28
First Reported 1992
Last Reported 2006
Negated 0
Speculated 0
Reported most in Body
Documents 2
Total Number 2
Disease Relevance 0.83
Pain Relevance 0.22

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

cell differentiation (RASGRP1) Golgi apparatus (RASGRP1) endoplasmic reticulum (RASGRP1)
cytoplasm (RASGRP1) cytosol (RASGRP1) lipid binding (RASGRP1)
Anatomy Link Frequency
plasma 2
brain 2
RASGRP1 (Homo sapiens)
Pain Link Frequency Relevance Heat
antagonist 1 93.92 High High
Pain 2 85.28 High High
Neurotransmitter 1 74.36 Quite High
palliative 3 5.00 Very Low Very Low Very Low
dexamethasone 2 5.00 Very Low Very Low Very Low
Spinal cord 1 5.00 Very Low Very Low Very Low
Analgesic 1 5.00 Very Low Very Low Very Low
Intractable pain 1 5.00 Very Low Very Low Very Low
addiction 1 5.00 Very Low Very Low Very Low
Kinase C 1 5.00 Very Low Very Low Very Low
Disease Link Frequency Relevance Heat
Hypertension 5 100.00 Very High Very High Very High
Cancer 12 89.24 High High
Pain 2 85.28 High High
Apoptosis 8 73.04 Quite High
Lung Cancer 2 68.32 Quite High
Breast Cancer 25 50.00 Quite Low
Metastasis 11 49.52 Quite Low
Malignant Neoplastic Disease 3 41.48 Quite Low
Bone Cancer 3 39.24 Quite Low
Hypercalcemia 3 36.36 Quite Low

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
Oral treatment with angiotensin-converting enzyme inhibitors, which interfere with the formation of angiotensin II, prevents the development of hypertension in young SHR by acting, at least in part, upon the brain RAS.
Negative_regulation (prevents) of RAS Binding (acting) of in brain associated with hypertension
1) Confidence 0.28 Published 1992 Journal Brain Res. Brain Res. Rev. Section Abstract Doc Link 1361394 Disease Relevance 0.55 Pain Relevance 0.17
The blockade of Ras binding to the plasma membrane may therefore be a good therapeutic target for the treatment of malignancies [22].
Negative_regulation (blockade) of Ras Binding (binding) of in plasma
2) Confidence 0.14 Published 2006 Journal Breast Cancer Res Section Body Doc Link PMC1779467 Disease Relevance 0.28 Pain Relevance 0.05

General Comments

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