INT80807

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Context Info
Confidence 0.38
First Reported 1999
Last Reported 2010
Negated 1
Speculated 0
Reported most in Abstract
Documents 3
Total Number 3
Disease Relevance 1.78
Pain Relevance 0.90

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

cytosol (PDC) nucleus (PDC) cilium (PDC)
cytoplasm (PDC)
PDC (Homo sapiens)
Pain Link Frequency Relevance Heat
opioid receptor 4 98.30 Very High Very High Very High
ASIC 5 95.04 Very High Very High Very High
Enkephalin 3 88.96 High High
psoriasis 22 85.04 High High
Opioid 7 82.40 Quite High
chemokine 7 81.68 Quite High
cytokine 9 68.96 Quite High
Central nervous system 1 57.12 Quite High
Pain 2 51.04 Quite High
Inflammation 20 41.40 Quite Low
Disease Link Frequency Relevance Heat
Cerebral Palsy 7 100.00 Very High Very High Very High
Psoriasis 40 93.84 High High
Neurological Disease 2 81.52 Quite High
Disease 20 79.40 Quite High
Movement Disorders 1 77.16 Quite High
Dystonia 2 75.44 Quite High
Stress 14 57.92 Quite High
Pain 1 51.04 Quite High
INFLAMMATION 22 41.40 Quite Low
Necrosis 1 37.48 Quite Low

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
Because the internalization of opioid receptors as well as the activity of adenylyl cyclase (AC) activity depends on G proteins, we tested Phd on these parameters.
Positive_regulation (tested) of Phd associated with opioid receptor
1) Confidence 0.38 Published 1999 Journal J. Pharmacol. Exp. Ther. Section Abstract Doc Link 10087055 Disease Relevance 0 Pain Relevance 0.38
In humans, infiltration of pDC and expression of IFN-?
Positive_regulation (infiltration) of pDC
2) Confidence 0.25 Published 2010 Journal Mediators of Inflammation Section Body Doc Link PMC2929514 Disease Relevance 0.80 Pain Relevance 0.29
Therefore, although the ASIC4 gene is physically mapped to the PDC locus, our data indicates that ASIC4 gene mutation is not the cause of PDC.
Neg (not) Positive_regulation (cause) of PDC associated with cerebral palsy
3) Confidence 0.17 Published 2001 Journal Eur. J. Hum. Genet. Section Abstract Doc Link 11571555 Disease Relevance 0.97 Pain Relevance 0.23

General Comments

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