INT8088

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Context Info
Confidence 0.60
First Reported 1980
Last Reported 2002
Negated 1
Speculated 1
Reported most in Abstract
Documents 28
Total Number 29
Disease Relevance 2.37
Pain Relevance 13.91

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

extracellular region (Cga) molecular_function (Cga) cellular_component (Cga)
biological_process (Cga)
Anatomy Link Frequency
pituitary 26
anterior pituitary 19
nucleus 4
external 4
brain 3
Cga (Rattus norvegicus)
Pain Link Frequency Relevance Heat
narcan 30 100.00 Very High Very High Very High
antagonist 23 100.00 Very High Very High Very High
Opioid 21 100.00 Very High Very High Very High
withdrawal 3 99.98 Very High Very High Very High
opiate 30 99.82 Very High Very High Very High
Morphine 40 99.76 Very High Very High Very High
analgesia 1 99.68 Very High Very High Very High
Dynorphin 6 99.40 Very High Very High Very High
depression 12 99.36 Very High Very High Very High
Neuropeptide 10 99.16 Very High Very High Very High
Disease Link Frequency Relevance Heat
Fever 1 99.96 Very High Very High Very High
Aging 7 99.84 Very High Very High Very High
Depression 12 99.36 Very High Very High Very High
Body Weight 3 89.76 High High
Stress 4 80.56 Quite High
Urological Neuroanatomy 8 77.20 Quite High
Duodenal Ulcer 4 75.00 Quite High
Peptic Ulcer 1 70.16 Quite High
Feminization 1 40.88 Quite Low

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
Neuropeptide Y: a novel neuroendocrine peptide in the control of pituitary hormone secretion, and its relation to luteinizing hormone.
Regulation (control) of Localization (secretion) of pituitary hormone in pituitary associated with neuropeptide
1) Confidence 0.60 Published 1992 Journal Front Neuroendocrinol Section Title Doc Link 1361458 Disease Relevance 0 Pain Relevance 0.10
The effect of d-fenfluramine on anterior pituitary hormone release in the rat: in vivo and in vitro studies.
Regulation (effect) of Localization (release) of pituitary hormone in anterior pituitary
2) Confidence 0.60 Published 1987 Journal Can. J. Physiol. Pharmacol. Section Title Doc Link 3449200 Disease Relevance 0 Pain Relevance 0.25
The effects of chronic naloxone on pituitary hormone secretion in female rats.
Regulation (effects) of Localization (secretion) of pituitary hormone in pituitary associated with narcan
3) Confidence 0.60 Published 1984 Journal Brain Res. Bull. Section Title Doc Link 6329481 Disease Relevance 0.08 Pain Relevance 0.66
Role of central epinephrine in regulation of anterior pituitary hormone secretion.
Regulation (Role) of Localization (secretion) of pituitary hormone in anterior pituitary
4) Confidence 0.60 Published 1982 Journal Peptides Section Title Doc Link 6750566 Disease Relevance 0 Pain Relevance 0.19
Although not yet fully established, there is growing evidence that the EOP participate in the physiological regulation of pituitary hormone secretion.
Regulation (participate) of Localization (secretion) of pituitary hormone in pituitary
5) Confidence 0.60 Published 1980 Journal Fed. Proc. Section Abstract Doc Link 6247213 Disease Relevance 0.08 Pain Relevance 0.73
Influence of morphine during pregnancy on neuroendocrine regulation of pituitary hormone secretion.
Regulation (regulation) of Localization (secretion) of pituitary hormone in pituitary associated with morphine
6) Confidence 0.60 Published 1983 Journal J. Endocrinol. Section Title Doc Link 6875436 Disease Relevance 0 Pain Relevance 0.72
Neuropeptides present in the PVN and presumably in nerve fibers of the external layer of the median eminence may participate in the control of the anterior pituitary hormone secretion.
Spec (may) Regulation (participate) of Localization (secretion) of pituitary hormone in external associated with neuropeptide
7) Confidence 0.60 Published 1989 Journal Neuroendocrinology Section Abstract Doc Link 2469987 Disease Relevance 0 Pain Relevance 0.52
The administration of morphine or opioid peptides produces alterations in the neuroendocrine regulation of anterior pituitary hormone secretion, including the depression of serum levels of luteinizing hormone (LH).
Regulation (regulation) of Localization (secretion) of pituitary hormone in anterior pituitary associated with depression, opioid and morphine
8) Confidence 0.60 Published 1981 Journal Neuroendocrinology Section Abstract Doc Link 7022252 Disease Relevance 0.47 Pain Relevance 0.71
The high ratio of expression of NO in magnocellular neurosecretory dynorphin containing neurons suggested that NO participates in controlling posterior pituitary hormone secretion together with dynorphin.
Regulation (controlling) of Localization (secretion) of pituitary hormone in posterior pituitary associated with dynorphin
9) Confidence 0.60 Published 1994 Journal Nippon Naibunpi Gakkai Zasshi Section Abstract Doc Link 7528149 Disease Relevance 0 Pain Relevance 0.59
In an attempt to elucidate the effects of norepinephrine on the central control of pituitary hormone secretion, we looked at the actions of norepinephrine on the electrical properties of putative parvocellular neurons of the paraventricular nucleus using whole-cell current-clamp recordings in hypothalamic slices.
Regulation (effects) of Localization (secretion) of pituitary hormone in nucleus
10) Confidence 0.60 Published 2000 Journal Neuroscience Section Abstract Doc Link 10727792 Disease Relevance 0 Pain Relevance 0
Evidence that establishes neuropeptide Y (NPY) as an important neuromessenger in the regulation of anterior pituitary hormone secretion is reviewed.
Regulation (regulation) of Localization (secretion) of pituitary hormone in anterior pituitary associated with neuropeptide
11) Confidence 0.60 Published 1992 Journal Front Neuroendocrinol Section Abstract Doc Link 1361458 Disease Relevance 0 Pain Relevance 0.09
The peptide injected into the cerebrospinal fluid (CSF) produces a wide spectrum of biological effects including analgesia, hyperthermia, changes in pituitary hormone release, decrease in food and water intake, locomotor activity, and blood pressure.
Regulation (changes) of Localization (release) of pituitary hormone in pituitary associated with eae, fever and analgesia
12) Confidence 0.60 Published 1987 Journal Life Sci. Section Abstract Doc Link 3600197 Disease Relevance 0.44 Pain Relevance 0.36
The effects of neurotensin on anterior pituitary hormone secretion.
Regulation (effects) of Localization (secretion) of pituitary hormone in anterior pituitary
13) Confidence 0.44 Published 1982 Journal Ann. N. Y. Acad. Sci. Section Title Doc Link 6820240 Disease Relevance 0 Pain Relevance 0.15
Although it has long been known that opioid peptides cause marked changes of pituitary hormone secretion in both animals and humans, little is known about the possible effect(s) of food-derived opioids (exorphins) on pituitary function.
Regulation (changes) of Localization (secretion) of pituitary hormone in pituitary associated with opioid
14) Confidence 0.44 Published 2002 Journal Life Sci. Section Abstract Doc Link 12231399 Disease Relevance 0 Pain Relevance 0.55
Although not yet fully established, there is growing evidence that the EOP participate in the physiological regulation of pituitary hormone secretion.
Regulation (regulation) of Localization (secretion) of pituitary hormone in pituitary
15) Confidence 0.26 Published 1980 Journal Fed. Proc. Section Abstract Doc Link 6247213 Disease Relevance 0.08 Pain Relevance 0.73
In an attempt to elucidate the effects of norepinephrine on the central control of pituitary hormone secretion, we looked at the actions of norepinephrine on the electrical properties of putative parvocellular neurons of the paraventricular nucleus using whole-cell current-clamp recordings in hypothalamic slices.
Regulation (control) of Localization (secretion) of pituitary hormone in nucleus
16) Confidence 0.26 Published 2000 Journal Neuroscience Section Abstract Doc Link 10727792 Disease Relevance 0 Pain Relevance 0
Morphine withdrawal alters anterior pituitary hormone secretion, brain endopeptidase activity and brain monoamine metabolism in the rat.
Regulation (alters) of in brain Localization (secretion) of pituitary hormone in anterior pituitary associated with withdrawal, monoamine and morphine
17) Confidence 0.26 Published 1996 Journal Pharmacol. Toxicol. Section Title Doc Link 8882344 Disease Relevance 0.15 Pain Relevance 0.56
It is well established that hypothalamic galanin- and beta-endorphin-containing circuits play important roles in the neuroendocrine regulation of pituitary hormone secretion and sexual behaviors, as well as in feeding.
Regulation (regulation) of Localization (secretion) of pituitary hormone in pituitary
18) Confidence 0.26 Published 1995 Journal J. Neuroendocrinol. Section Abstract Doc Link 8704731 Disease Relevance 0 Pain Relevance 0.17
The administration of morphine or opioid peptides produces alterations in the neuroendocrine regulation of anterior pituitary hormone secretion, including the depression of serum levels of luteinizing hormone (LH).
Regulation (alterations) of Localization (secretion) of pituitary hormone in anterior pituitary associated with depression, opioid and morphine
19) Confidence 0.26 Published 1981 Journal Neuroendocrinology Section Abstract Doc Link 7022252 Disease Relevance 0.47 Pain Relevance 0.71
Neuropeptides present in the PVN and presumably in nerve fibers of the external layer of the median eminence may participate in the control of the anterior pituitary hormone secretion.
Regulation (control) of Localization (secretion) of pituitary hormone in external associated with neuropeptide
20) Confidence 0.26 Published 1989 Journal Neuroendocrinology Section Abstract Doc Link 2469987 Disease Relevance 0 Pain Relevance 0.52

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