INT80902

From wiki-pain
Jump to: navigation, search
Context Info
Confidence 0.25
First Reported 1999
Last Reported 2010
Negated 0
Speculated 0
Reported most in Body
Documents 4
Total Number 4
Disease Relevance 1.82
Pain Relevance 3.56

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

nucleoplasm (Adarb1) mRNA processing (Adarb1) nucleolus (Adarb1)
RNA binding (Adarb1) nucleus (Adarb1) intracellular (Adarb1)
Anatomy Link Frequency
follicle 2
dorsal horn 2
hindbrain 2
Adarb1 (Rattus norvegicus)
Pain Link Frequency Relevance Heat
mu opioid receptor 3 100.00 Very High Very High Very High
gABA 1 100.00 Very High Very High Very High
ischemia 6 99.98 Very High Very High Very High
Spinal cord 9 99.80 Very High Very High Very High
Dorsal horn 3 99.68 Very High Very High Very High
intrathecal 5 99.60 Very High Very High Very High
Pain 10 99.38 Very High Very High Very High
Neuropathic pain 3 98.92 Very High Very High Very High
antinociception 10 98.64 Very High Very High Very High
Nerve growth factor 9 98.20 Very High Very High Very High
Disease Link Frequency Relevance Heat
Gliosis 2 100.00 Very High Very High Very High
Spinal Cord Ischemia 3 99.98 Very High Very High Very High
Neuropathic Pain 11 98.92 Very High Very High Very High
Cv Unclassified Under Development 3 96.84 Very High Very High Very High
Generalized Anxiety Disorder 1 93.28 High High
Injury 8 84.24 Quite High
Hyperalgesia 4 82.28 Quite High
INFLAMMATION 6 66.28 Quite High
Nociception 20 50.00 Quite Low
Pain 8 33.52 Quite Low

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
The results indicate that spinal cord ischemia reduces the expression of mu-opioid receptors in rat dorsal horn, which may be one of the underlying mechanisms of morphine insensitivity for treating acute allodynia after spinal ischemia.
Negative_regulation (reduces) of Gene_expression (expression) of receptors in dorsal horn associated with allodynia, ischemia, dorsal horn, mu opioid receptor, morphine and spinal cord
1) Confidence 0.25 Published 1999 Journal Neuroreport Section Abstract Doc Link 10094139 Disease Relevance 0.78 Pain Relevance 1.50
-methylene-ATP-induced antinociception by repeated i.c.v. pretreatments with P2X3 A-ODN is attributed to the decreased expression of P2X3 receptors in the hindbrain.
Negative_regulation (he decrea) of Gene_expression (ed express) of receptors in hindbrain associated with antinociception
2) Confidence 0.02 Published 2006 Journal Mol Pain Section Body Doc Link PMC1557483 Disease Relevance 0.13 Pain Relevance 0.76
Intrathecal NGF administration reduces reactive astrocytosis and changes neurotrophin receptors expression pattern in a rat model of neuropathic pain.
Negative_regulation (reduces) of Gene_expression (expression) of receptors associated with neuropathic pain, gliosis and intrathecal
3) Confidence 0.01 Published 2010 Journal Cell. Mol. Neurobiol. Section Title Doc Link 19585233 Disease Relevance 0.81 Pain Relevance 1.12
By contrast, seven days of whisker-deprivation in adult rats reduces expression of GABA-A receptors in the barrel cortex (Fuchs and Salazar, 1998), as does whisker follicle lesioning in adult mice (Skangiel-Kramska et al., 1994).
Negative_regulation (reduces) of Gene_expression (expression) of receptors in follicle associated with gaba
4) Confidence 0.01 Published 2006 Journal Neuroscience Section Body Doc Link PMC2860223 Disease Relevance 0.09 Pain Relevance 0.17

General Comments

This test has worked.

Personal tools
Namespaces

Variants
Actions
Navigation
Toolbox