INT81004

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Context Info
Confidence 0.20
First Reported 1999
Last Reported 1999
Negated 0
Speculated 0
Reported most in Abstract
Documents 1
Total Number 1
Disease Relevance 0
Pain Relevance 0.50

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

Golgi apparatus (Gtpbp4) GTPase activity (Gtpbp4) ribosome biogenesis (Gtpbp4)
cytoplasm (Gtpbp4) signal transducer activity (Htr1a) nucleolus (Gtpbp4)
Anatomy Link Frequency
brain 1
Htr1a (Rattus norvegicus)
Gtpbp4 (Rattus norvegicus)
Pain Link Frequency Relevance Heat
agonist 5 97.76 Very High Very High Very High
Sumatriptan 11 94.00 High High
Hippocampus 1 53.28 Quite High
Substantia nigra 6 52.00 Quite High
antagonist 2 42.56 Quite Low

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Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
The present study reports on G-protein activation by recombinant 5-HT receptors and by native 5-HT1A and 5-HT1B receptors in guinea-pig and rat brain using agonist-stimulated [35S]GTPgammaS binding responses mediated by a new 5-HT ligand, a dimer of sumatriptan.
5-HT1A Positive_regulation (activation) of G-protein in brain associated with sumatriptan and agonist
1) Confidence 0.20 Published 1999 Journal Brain Res. Mol. Brain Res. Section Abstract Doc Link 10101238 Disease Relevance 0 Pain Relevance 0.50

General Comments

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