INT81061

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Context Info
Confidence 0.22
First Reported 1999
Last Reported 1999
Negated 1
Speculated 0
Reported most in Abstract
Documents 1
Total Number 1
Disease Relevance 0
Pain Relevance 0.53

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

nucleus (Egr1) intracellular (Egr1) DNA binding (Egr1)
transcription factor binding (Egr1) cytoplasm (Egr1)
Anatomy Link Frequency
caudate-putamen 2
Egr1 (Rattus norvegicus)
Pain Link Frequency Relevance Heat
Enkephalin 3 99.50 Very High Very High Very High
cocaine 1 88.12 High High
agonist 3 87.76 High High
Dopamine 5 87.44 High High
Nucleus accumbens 1 70.96 Quite High
antagonist 1 51.76 Quite High

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Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
In situ hybridization experiments in the caudate-putamen indicated that SR48692 (10 mg/kg) markedly reduced zif268 mRNA labelling produced by SKF38393 plus quinpirole in cells not expressing enkephalin mRNA, but was unable to affect the concomitant decrease of zif268 mRNA labelling in enkephalin-positive cells.
Neg (unable) Regulation (affect) of Negative_regulation (decrease) of zif268 mRNA in caudate-putamen associated with enkephalin
1) Confidence 0.22 Published 1999 Journal Eur. J. Neurosci. Section Abstract Doc Link 10103090 Disease Relevance 0 Pain Relevance 0.53

General Comments

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