INT81099

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Context Info
Confidence 0.09
First Reported 1999
Last Reported 1999
Negated 0
Speculated 0
Reported most in Abstract
Documents 1
Total Number 1
Disease Relevance 1.29
Pain Relevance 0.13

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

Pol1 (Mus musculus)
Pain Link Frequency Relevance Heat
Bioavailability 1 76.28 Quite High
Post herpetic neuralgia 1 59.84 Quite High
Shingles 1 54.52 Quite High
neuralgia 1 25.00 Low Low
Disease Link Frequency Relevance Heat
Infection 5 83.88 Quite High
Herpes Zoster 16 83.44 Quite High
Sprains And Strains 1 79.12 Quite High
Cancer 1 64.96 Quite High
Acquired Immune Deficiency Syndrome Or Hiv Infection 1 63.56 Quite High
Neuralgia 2 59.84 Quite High
Herpes Simplex Virus Infection 1 59.44 Quite High
Chronic Disease 1 25.00 Low Low
Leukemia 1 25.00 Low Low

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
As with aciclovir itself, all of these drugs are dependent on the virus-encoded thymidine kinase (TK) for their intracellular activation (phosphorylation), and, upon conversion to their triphosphate form, they act as inhibitors/alternative substrate of the viral DNA polymerase.
Positive_regulation (substrate) of viral DNA polymerase
1) Confidence 0.09 Published 1999 Journal Drugs Section Abstract Doc Link 10188760 Disease Relevance 1.29 Pain Relevance 0.13

General Comments

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