INT81267

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Context Info
Confidence 0.02
First Reported 1999
Last Reported 1999
Negated 0
Speculated 0
Reported most in Abstract
Documents 1
Total Number 1
Disease Relevance 0.28
Pain Relevance 0.56

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

nucleoplasm (NCOR2) small molecule metabolic process (NCOR2) extracellular region (MLN)
nucleolus (NCOR2) nucleus (NCOR2) DNA binding (NCOR2)
Anatomy Link Frequency
smooth muscle 2
MLN (Homo sapiens)
NCOR2 (Homo sapiens)
Pain Link Frequency Relevance Heat
agonist 3 97.92 Very High Very High Very High
antagonist 4 88.52 High High
Cholecystokinin 1 82.80 Quite High
spastic colon 11 75.00 Quite High
Pain 2 74.80 Quite High
Calcium channel 1 71.68 Quite High
Disease Link Frequency Relevance Heat
Constipation 2 95.84 Very High Very High Very High
Functional Bowel Disorder 2 75.00 Quite High
Irritable Bowel Syndrome /

Irritable Bowel Syndrome Super

10 58.68 Quite High
Pain 1 46.16 Quite Low
Congenital Anomalies 1 36.40 Quite Low
Diarrhoea 1 25.00 Low Low

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
Erythromycin and related 14-member macrolide compounds inhibit the binding of motilin to its receptors on GI smooth muscle and, therefore, act as motilin agonists.
Negative_regulation (inhibit) of motilin Binding (binding) of receptors in smooth muscle associated with agonist
1) Confidence 0.02 Published 1999 Journal Can. J. Gastroenterol. Section Abstract Doc Link 10202210 Disease Relevance 0.17 Pain Relevance 0.56

General Comments

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