INT81353

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Context Info
Confidence 0.68
First Reported 1999
Last Reported 2009
Negated 0
Speculated 0
Reported most in Abstract
Documents 2
Total Number 2
Disease Relevance 1.89
Pain Relevance 0.24

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

transport (Fmr1) nucleolus (Fmr1) RNA binding (Fmr1)
nucleus (Fmr1) cytoplasm (Fmr1)
Anatomy Link Frequency
muscle 1
lymphocytes 1
Fmr1 (Rattus norvegicus)
Pain Link Frequency Relevance Heat
Pain 1 97.76 Very High Very High Very High
Fibrositis 1 79.72 Quite High
peripheral neuropathy 1 79.00 Quite High
fluoxetine 1 63.92 Quite High
Disease Link Frequency Relevance Heat
Intellectual Impairment 1 100.00 Very High Very High Very High
Turner's Syndrome 4 99.36 Very High Very High Very High
Thyroid Disease 2 99.16 Very High Very High Very High
Myalgia 1 98.04 Very High Very High Very High
Syndrome 7 91.28 High High
Learning Disorders 1 84.56 Quite High
Sleep Disorders 1 79.72 Quite High
Peripheral Neuropathy 1 79.00 Quite High
Convulsion 1 78.08 Quite High
Hypertension 1 77.68 Quite High

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
Immunocytochemistry of blood smears showed fragile X mental retardation-1 protein (FMRP) expression in 63.5% of lymphocytes.
Gene_expression (expression) of fragile X mental retardation-1 protein in lymphocytes associated with intellectual impairment
1) Confidence 0.68 Published 1999 Journal Am. J. Med. Genet. Section Abstract Doc Link 10208169 Disease Relevance 0.64 Pain Relevance 0.06
Furthermore, among females with the FMR1 premutation, penetrance of POI, thyroid disease and chronic muscle pain is 18.6, 15.9 and 24.4%, respectively.
Gene_expression (premutation) of FMR1 in muscle associated with pain, thyroid disease, turner's syndrome and myalgia
2) Confidence 0.63 Published 2009 Journal Eur. J. Hum. Genet. Section Abstract Doc Link 19367323 Disease Relevance 1.25 Pain Relevance 0.18

General Comments

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