INT81383

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Context Info
Confidence 0.36
First Reported 1999
Last Reported 2010
Negated 0
Speculated 0
Reported most in Body
Documents 2
Total Number 2
Disease Relevance 0.31
Pain Relevance 0.09

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

endoplasmic reticulum (FLT3)
Anatomy Link Frequency
bone marrow 1
stem 1
FLT3 (Homo sapiens)
Pain Link Frequency Relevance Heat
anesthesia 1 89.68 High High
ischemia 12 5.00 Very Low Very Low Very Low
Inflammation 8 5.00 Very Low Very Low Very Low
Central nervous system 6 5.00 Very Low Very Low Very Low
Dopamine 3 5.00 Very Low Very Low Very Low
cytokine 3 5.00 Very Low Very Low Very Low
Spinal cord 2 5.00 Very Low Very Low Very Low
gABA 2 5.00 Very Low Very Low Very Low
cva 2 5.00 Very Low Very Low Very Low
Inflammatory response 2 5.00 Very Low Very Low Very Low
Disease Link Frequency Relevance Heat
Breast Cancer 3 87.32 High High
Brain Injury 9 68.28 Quite High
Hematologic Neoplasms 3 46.32 Quite Low
Leukemia 1 29.28 Quite Low
Disease 14 14.68 Low Low
Brain Hemorrhage 39 5.00 Very Low Very Low Very Low
Neurodegenerative Disease 12 5.00 Very Low Very Low Very Low
INFLAMMATION 10 5.00 Very Low Very Low Very Low
Heat Stroke 6 5.00 Very Low Very Low Very Low
Injury 6 5.00 Very Low Very Low Very Low

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
The bone marrow cultures, which included the stromal cells collected with the aspirate, were supplemented with erythropoietin, granulocyte-macrophage-colony stimulating factor (GM-CSF)/IL-3 fusion protein (PIXY 321), and flt3 ligand.
flt3 Binding (supplemented) of in bone marrow
1) Confidence 0.36 Published 1999 Journal Exp. Hematol. Section Abstract Doc Link 10210319 Disease Relevance 0.25 Pain Relevance 0.09
For instance, McGuckin et al. demonstrated the presence of embryonic stem (ES)-like cells in CB, from which under expansion with thrombopoietin, flt-3, and c-kit ligand, slow-dividing adherent cell populations resulted with neuroglial progenitor morphology, upregulation of primitive neuroglial cell markers, and expression of glial fibrillary acidic protein (GFAP) [26].
flt-3 Binding (expansion) of in stem
2) Confidence 0.10 Published 2010 Journal International Journal of Molecular Sciences Section Body Doc Link PMC2956109 Disease Relevance 0.07 Pain Relevance 0

General Comments

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