INT8141

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Context Info
Confidence 0.14
First Reported 1992
Last Reported 2010
Negated 0
Speculated 0
Reported most in Body
Documents 2
Total Number 3
Disease Relevance 0.92
Pain Relevance 1.24

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

OR5D2P (Homo sapiens)
Pain Link Frequency Relevance Heat
opioid receptor 4 100.00 Very High Very High Very High
Dynorphin 1 100.00 Very High Very High Very High
Enkephalin 2 99.96 Very High Very High Very High
Opioid 6 96.32 Very High Very High Very High
Pain 16 92.24 High High
depression 4 91.12 High High
Potency 2 90.24 High High
antagonist 2 81.04 Quite High
Osteoarthritis 46 70.28 Quite High
cocaine 1 65.76 Quite High
Disease Link Frequency Relevance Heat
Pain 18 92.24 High High
Anxiety Disorder 4 91.44 High High
Depression 4 91.12 High High
Frailty 50 70.28 Quite High
Arthritis 8 41.92 Quite Low
Disease 6 5.00 Very Low Very Low Very Low
Rheumatoid Arthritis 6 5.00 Very Low Very Low Very Low
Low Back Pain 2 5.00 Very Low Very Low Very Low
Overweight 2 5.00 Very Low Very Low Very Low
Fibromyalgia 2 5.00 Very Low Very Low Very Low

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
There were statistically significant differences between the two groups in EQ5D levels in the five dimensions, with the intervention group having a higher proportion of patients in level 1 (no problems) after 6 months in all the dimensions (mobility, self-care, usual activities, pain/discomfort and anxiety/depression) (p < 0.001).
Gene_expression (levels) of EQ5D associated with pain, depression and anxiety disorder
1) Confidence 0.14 Published 2010 Journal BMC Musculoskelet Disord Section Body Doc Link PMC2987970 Disease Relevance 0.35 Pain Relevance 0.17
The EQ5D can be presented as a health profile or as a global health index with a weighted total value (British tariff used), where the minimum value is -0.594 and the maximum 1.0 [19].
Gene_expression (presented) of EQ5D
2) Confidence 0.09 Published 2010 Journal BMC Musculoskelet Disord Section Body Doc Link PMC2987970 Disease Relevance 0.57 Pain Relevance 0.32
These peptides were prototypic for opioid receptors of the following types: kappa [dynorphin(1-13)], mu (DAMGO) H-Tyr-D-Ala2-Gly-N-Me-Phe-Gly5- ol, and delta (DPDPE) H-Tyr-O-Pen-Gly-Phe-D-Pen-OH[D-Pen2,D-Pen5]enkephalin.
Gene_expression (prototypic) of D-Pen5 associated with dynorphin, enkephalin and opioid receptor
3) Confidence 0.02 Published 1992 Journal Peptides Section Abstract Doc Link 1362265 Disease Relevance 0 Pain Relevance 0.75

General Comments

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