INT81577

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Context Info
Confidence 0.26
First Reported 1999
Last Reported 2007
Negated 0
Speculated 0
Reported most in Body
Documents 3
Total Number 3
Disease Relevance 0.82
Pain Relevance 0.48

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

extracellular space (ALPL) plasma membrane (ALPL)
Anatomy Link Frequency
granulocyte 1
ALPL (Homo sapiens)
Pain Link Frequency Relevance Heat
Pain 15 100.00 Very High Very High Very High
medulla 1 93.20 High High
Locus ceruleus 1 90.88 High High
cINOD 25 76.84 Quite High
Arthritis 1 67.60 Quite High
Clonidine 48 50.00 Quite Low
agonist 3 50.00 Quite Low
Inflammation 6 5.00 Very Low Very Low Very Low
visual analogue scale 2 5.00 Very Low Very Low Very Low
cva 2 5.00 Very Low Very Low Very Low
Disease Link Frequency Relevance Heat
Pain 14 98.96 Very High Very High Very High
Cognitive Disorder 10 93.04 High High
Phosphate Metabolism Disorders 55 90.96 High High
Arthritis 1 67.60 Quite High
INFLAMMATION 8 28.16 Quite Low
Fatigue 5 5.00 Very Low Very Low Very Low
Cv General 3 Under Development 2 5.00 Very Low Very Low Very Low
Disorders Of Creatine Metabolism 1 5.00 Very Low Very Low Very Low
Congenital Anomalies 1 5.00 Very Low Very Low Very Low
Intellectual Impairment 1 5.00 Very Low Very Low Very Low

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
There are biochemical [5] and molecular data [6-9] indicating that the severity of the molecular genetic alterations and subsequent changes in the levels of TNSALP are major determinants of the clinical phenotype.
Regulation (changes) of TNSALP
1) Confidence 0.26 Published 2006 Journal Orphanet J Rare Dis Section Body Doc Link PMC1533806 Disease Relevance 0.62 Pain Relevance 0.11
Changes in serum osteocalcin and bone-specific alkaline phosphatase are associated with bone pain in donors receiving granulocyte-colony-stimulating factor for peripheral blood stem and progenitor cell collection.
Regulation (Changes) of bone-specific alkaline phosphatase in granulocyte associated with pain
2) Confidence 0.04 Published 1999 Journal Transfusion Section Title Doc Link 10220269 Disease Relevance 0.10 Pain Relevance 0.28
The conventional view of NE is that it has broad, nonspecific functions such as regulating arousal (Jouvet 1969).
Regulation (regulating) of nonspecific
3) Confidence 0.03 Published 2007 Journal Psychopharmacology (Berl) Section Body Doc Link PMC1915624 Disease Relevance 0.09 Pain Relevance 0.09

General Comments

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