INT81597

From wiki-pain
Jump to: navigation, search
Context Info
Confidence 0.69
First Reported 1999
Last Reported 2004
Negated 0
Speculated 0
Reported most in Abstract
Documents 10
Total Number 10
Disease Relevance 5.52
Pain Relevance 8.53

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

extracellular space (Npff) extracellular region (Npff)
Anatomy Link Frequency
spinal cord 2
spinal 1
neuronal 1
area postrema 1
brain 1
Npff (Rattus norvegicus)
Pain Link Frequency Relevance Heat
Morphine 8 99.92 Very High Very High Very High
Spinal cord 18 99.74 Very High Very High Very High
Dorsal horn 4 99.68 Very High Very High Very High
Central nervous system 6 99.56 Very High Very High Very High
Analgesic 1 99.12 Very High Very High Very High
Neuropathic pain 10 98.60 Very High Very High Very High
intrathecal 4 97.88 Very High Very High Very High
IPN 5 97.72 Very High Very High Very High
fifth nerve 3 97.40 Very High Very High Very High
Inflammation 8 96.96 Very High Very High Very High
Disease Link Frequency Relevance Heat
Neuropathic Pain 21 98.60 Very High Very High Very High
Inflammatory Pain 5 97.72 Very High Very High Very High
INFLAMMATION 8 96.96 Very High Very High Very High
Pain 34 95.28 Very High Very High Very High
Cv Unclassified Under Development 4 94.56 High High
Nociception 6 87.32 High High
Urological Neuroanatomy 1 62.16 Quite High

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
Furthermore, we studied the mRNA levels of both NPFF and NPFF2 receptor in morphine-tolerant rats and after acute morphine injections.
Transcription (levels) of NPFF associated with morphine
1) Confidence 0.69 Published 2004 Journal Neurobiol. Dis. Section Abstract Doc Link 15207282 Disease Relevance 1.05 Pain Relevance 1.46
Significantly greater numbers of activated neurons expressing the NPFF gene (double labeled) were observed in the NTS at the level of the area postrema in animals receiving i.c.v.
Transcription (level) of NPFF gene in area postrema
2) Confidence 0.69 Published 2002 Journal J. Comp. Neurol. Section Abstract Doc Link 11984823 Disease Relevance 0.08 Pain Relevance 0.11
We confirm the validity of the in situ hybridization by showing that its distribution in the brain and spinal cord matches the distribution of NPFF and NPSF immunoreactivity.
Transcription (distribution) of NPFF in spinal cord associated with spinal cord
3) Confidence 0.67 Published 1999 Journal Mol. Pharmacol. Section Abstract Doc Link 10220558 Disease Relevance 0.39 Pain Relevance 0.84
NPFF mRNA expression is upregulated in the dorsal horn of the spinal cord after carrageenan-induced inflammation in the hind paw of the rat, but not in the neuropathic pain model induced by ligation of the spinal roots.
Transcription (expression) of NPFF in dorsal horn associated with inflammation, neuropathic pain, dorsal horn and spinal cord
4) Confidence 0.53 Published 1999 Journal Brain Res. Section Abstract Doc Link 10612711 Disease Relevance 0.58 Pain Relevance 1.07
Brains were prepared for Fos immunohistochemistry to identify neuronal activation and NPFF in situ hybridization to determine cells expressing NPFF mRNA in the NTS.
Transcription (expressing) of NPFF in neuronal
5) Confidence 0.53 Published 2002 Journal J. Comp. Neurol. Section Abstract Doc Link 11984823 Disease Relevance 0.16 Pain Relevance 0.24
We demonstrate that NPFF precursor mRNA expression by Northern analysis and map sites of expression by in situ hybridization.
Transcription (expression) of NPFF
6) Confidence 0.52 Published 1999 Journal Mol. Pharmacol. Section Abstract Doc Link 10220558 Disease Relevance 0.30 Pain Relevance 0.69
Of the peptides studied, only NPFF mRNA was found in the dorsal horn of the spinal cord and spinal nucleus of the trigeminal nerve.
Transcription (found) of NPFF in spinal associated with fifth nerve, dorsal horn and spinal cord
7) Confidence 0.46 Published 2004 Journal Neuropharmacology Section Abstract Doc Link 14975697 Disease Relevance 0.85 Pain Relevance 1.08
PrRP and NPFF mRNA were expressed in different parts of the nucleus of the solitary tract.
Transcription (expressed) of NPFF in nucleus
8) Confidence 0.39 Published 2004 Journal Neuropharmacology Section Abstract Doc Link 14975697 Disease Relevance 0.89 Pain Relevance 1.12
We confirm the validity of the in situ hybridization by showing that its distribution in the brain and spinal cord matches the distribution of NPFF and NPSF immunoreactivity.
Transcription (distribution) of NPFF in brain associated with spinal cord
9) Confidence 0.23 Published 1999 Journal Mol. Pharmacol. Section Abstract Doc Link 10220558 Disease Relevance 0.39 Pain Relevance 0.84
Of the peptides studied, only NPFF mRNA was found in the dorsal horn of the spinal cord and spinal nucleus of the trigeminal nerve.
Transcription (found) of NPFF in spinal cord associated with fifth nerve, dorsal horn and spinal cord
10) Confidence 0.16 Published 2004 Journal Neuropharmacology Section Abstract Doc Link 14975697 Disease Relevance 0.85 Pain Relevance 1.08

General Comments

This test has worked.

Personal tools
Namespaces

Variants
Actions
Navigation
Toolbox