INT81604

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Context Info
Confidence 0.63
First Reported 1999
Last Reported 2000
Negated 0
Speculated 0
Reported most in Abstract
Documents 2
Total Number 2
Disease Relevance 0.67
Pain Relevance 0.78

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

transmembrane transporter activity (SLC22A6) plasma membrane (SLC22A6) protein complex (SLC22A6)
transmembrane transport (SLC22A6)
Anatomy Link Frequency
renal proximal tubules 1
tubule 1
SLC22A6 (Homo sapiens)
Pain Link Frequency Relevance Heat
cINOD 13 92.08 High High
Potency 3 72.80 Quite High
Paracetamol 2 58.56 Quite High
Disease Link Frequency Relevance Heat
Nephrotoxicity 2 93.00 High High
INFLAMMATION 4 90.64 High High
Acquired Immune Deficiency Syndrome Or Hiv Infection 4 89.80 High High

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
It has been recently shown that adefovir is efficiently transported by the human renal organic anion transporter 1 (hOAT1), a membrane transport protein localized in the kidney, that presumably mediates the accumulation of adefovir in renal proximal tubules.
Transcription (transported) of hOAT1 in renal proximal tubules
1) Confidence 0.63 Published 2000 Journal J. Pharmacol. Exp. Ther. Section Abstract Doc Link 10991954 Disease Relevance 0.51 Pain Relevance 0.23
Organic anion transporter 1 (OAT1) is the para-aminohippurate (PAH) transporter in the basolateral membrane of the proximal tubule.
Transcription (transporter) of para-aminohippurate in tubule
2) Confidence 0.02 Published 1999 Journal Mol. Pharmacol. Section Abstract Doc Link 10220563 Disease Relevance 0.17 Pain Relevance 0.55

General Comments

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