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Context Info
Confidence 0.43
First Reported 1999
Last Reported 1999
Negated 0
Speculated 0
Reported most in Abstract
Documents 1
Total Number 1
Disease Relevance 0
Pain Relevance 0.44

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mitochondrion (Pla2g2a) extracellular space (Pla2g2a) endoplasmic reticulum (Pla2g2a)
Anatomy Link Frequency
vesicles 2
Pla2g2a (Rattus norvegicus)
Pain Link Frequency Relevance Heat
halothane 10 100.00 Very High Very High Very High
anesthesia 2 100.00 Very High Very High Very High
Dopamine 1 99.38 Very High Very High Very High


Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
These observations suggest that the release of retinal transmitters (dopamine, acetylcholine and others) is affected during halothane anesthesia, due to activation of PLA2 and enhanced fusogenic activity of vesicular membranes with plasma membrane and depletion of vesicles.
Regulation (affected) of Positive_regulation (activation) of PLA2 in vesicles associated with anesthesia, dopamine and halothane
1) Confidence 0.43 Published 1999 Journal J Ocul Pharmacol Ther Section Abstract Doc Link 10229494 Disease Relevance 0 Pain Relevance 0.44

General Comments

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