INT81765

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Context Info
Confidence 0.58
First Reported 1999
Last Reported 2010
Negated 1
Speculated 0
Reported most in Body
Documents 4
Total Number 14
Disease Relevance 9.49
Pain Relevance 7.76

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

Anatomy Link Frequency
CTS 1
Cts (Mus musculus)
Pain Link Frequency Relevance Heat
carpal tunnel syndrome 1255 100.00 Very High Very High Very High
Action potential 165 99.10 Very High Very High Very High
depression 7 97.92 Very High Very High Very High
headache 8 94.24 High High
peripheral neuropathy 11 69.64 Quite High
alcohol 11 69.48 Quite High
Migraine 3 68.00 Quite High
Pain 35 41.72 Quite Low
Hypoesthesia 11 34.36 Quite Low
ischemia 1 33.36 Quite Low
Disease Link Frequency Relevance Heat
Carpal Tunnel Syndrome 1290 100.00 Very High Very High Very High
Depression 7 97.92 Very High Very High Very High
Anxiety Disorder 9 97.32 Very High Very High Very High
Tension-type Headache 4 94.24 High High
Injury 69 87.72 High High
Neuropathic Pain 156 80.56 Quite High
Headache 5 75.00 Quite High
Motor Neuron Diseases 99 74.88 Quite High
Peripheral Neuropathy 11 69.64 Quite High
Handedness 11 61.44 Quite High

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
In aggregate, these studies suggest that CTS development is associated with elevated CTP.
Gene_expression (development) of CTS associated with carpal tunnel syndrome
1) Confidence 0.58 Published 2008 Journal BMC Musculoskelet Disord Section Body Doc Link PMC2569035 Disease Relevance 0.74 Pain Relevance 0.47
CONCLUSIONS: This study demonstrates that CTS can be present in non-epileptic children and adolescents; in the majority of subjects this EEG abnormality disappears spontaneously and only a small percentage of subjects who have persistence of this pattern develops rolandic epilepsy.


Gene_expression (present) of CTS in CTS
2) Confidence 0.52 Published 1999 Journal J Paediatr Child Health Section Body Doc Link 10234637 Disease Relevance 0 Pain Relevance 0
No significant differences in MUNEs were found between the mild and severe CTS groups regardless of the method of calculation.
Gene_expression (groups) of CTS associated with carpal tunnel syndrome
3) Confidence 0.26 Published 2010 Journal J Neuroeng Rehabil Section Body Doc Link PMC2928769 Disease Relevance 0.46 Pain Relevance 0.38
In this study there were significant differences in the all the CMAP amplitudes and the MUNEs between the severe CTS and healthy groups as well as the mild CTS and healthy groups.
Gene_expression (groups) of CTS associated with action potential and carpal tunnel syndrome
4) Confidence 0.26 Published 2010 Journal J Neuroeng Rehabil Section Body Doc Link PMC2928769 Disease Relevance 0.72 Pain Relevance 0.69
Mild CTS
Gene_expression (Mild) of CTS associated with carpal tunnel syndrome
5) Confidence 0.26 Published 2010 Journal J Neuroeng Rehabil Section Body Doc Link PMC2928769 Disease Relevance 0.36 Pain Relevance 0.45
Post hoc analysis revealed significant group differences in symptom severity between the healthy control group and both the mild (p < 0.05) and severe CTS groups (p < 0.05) and in functionality scores between the severe CTS group and the healthy control groups (p < 0.05).


Gene_expression (groups) of CTS associated with carpal tunnel syndrome
6) Confidence 0.26 Published 2010 Journal J Neuroeng Rehabil Section Body Doc Link PMC2928769 Disease Relevance 1.04 Pain Relevance 1.00
In this study there were significant differences in the all the CMAP amplitudes and the MUNEs between the severe CTS and healthy groups as well as the mild CTS and healthy groups.
Gene_expression (groups) of CTS associated with action potential and carpal tunnel syndrome
7) Confidence 0.26 Published 2010 Journal J Neuroeng Rehabil Section Body Doc Link PMC2928769 Disease Relevance 0.71 Pain Relevance 0.68
This result is not surprising since sensory loss is normally experienced before motor loss in CTS and as such, the sensory losses experienced in subjects with mild CTS would be similar to those sustained by individuals with severe CTS.
Gene_expression (severe) of CTS associated with carpal tunnel syndrome
8) Confidence 0.26 Published 2010 Journal J Neuroeng Rehabil Section Body Doc Link PMC2928769 Disease Relevance 1.08 Pain Relevance 0.96
As such, the larger MUP amplitude in the severe CTS group as compared to the mild CTS and control groups suggests that larger motor units were active during EMG signal detection which in turn may suggest that collateral sprouting may have occurred at some point prior to the study.
Gene_expression (amplitude) of CTS associated with carpal tunnel syndrome
9) Confidence 0.26 Published 2010 Journal J Neuroeng Rehabil Section Body Doc Link PMC2928769 Disease Relevance 0.52 Pain Relevance 0.37
The long MUP durations of the severe CTS group relative to the mild and control groups again suggests that the severe group was undergoing or had undergone collateral reinnervation [5].
Gene_expression (durations) of CTS associated with carpal tunnel syndrome
10) Confidence 0.26 Published 2010 Journal J Neuroeng Rehabil Section Body Doc Link PMC2928769 Disease Relevance 0.74 Pain Relevance 0.58
Subjects were then stratified by CTS severity using the following criteria:
Gene_expression (severity) of CTS associated with carpal tunnel syndrome
11) Confidence 0.26 Published 2010 Journal J Neuroeng Rehabil Section Body Doc Link PMC2928769 Disease Relevance 0.40 Pain Relevance 0.47
The MUNE values for the mild and severe CTS groups are biased to low values because of the higher level of %MVC produced during EMG signal detection and are not anatomically accurate.
Gene_expression (produced) of CTS associated with carpal tunnel syndrome
12) Confidence 0.26 Published 2010 Journal J Neuroeng Rehabil Section Body Doc Link PMC2928769 Disease Relevance 0.49 Pain Relevance 0.43
Severe CTS
Gene_expression (Severe) of CTS associated with carpal tunnel syndrome
13) Confidence 0.26 Published 2010 Journal J Neuroeng Rehabil Section Body Doc Link PMC2928769 Disease Relevance 0.47 Pain Relevance 0.46
A significant negative correlation of PTS and CTS was observed in EM patients.
Neg (negative) Gene_expression (negative) of CTS
14) Confidence 0.11 Published 2004 Journal Pain Section Abstract Doc Link 15494185 Disease Relevance 1.76 Pain Relevance 0.83

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