INT81794

From wiki-pain
Jump to: navigation, search
Context Info
Confidence 0.39
First Reported 1999
Last Reported 2010
Negated 3
Speculated 0
Reported most in Body
Documents 12
Total Number 12
Disease Relevance 4.94
Pain Relevance 0.90

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

extracellular space (AGRP) extracellular region (AGRP) Golgi apparatus (AGRP)
Anatomy Link Frequency
skin 1
AGRP (Homo sapiens)
Pain Link Frequency Relevance Heat
alcohol 278 98.84 Very High Very High Very High
melanocortin 1 receptor 2 89.20 High High
antagonist 2 68.00 Quite High
depression 9 53.52 Quite High
cytokine 20 51.28 Quite High
cocaine 12 47.56 Quite Low
methadone 2 36.04 Quite Low
Central nervous system 21 5.00 Very Low Very Low Very Low
Inflammation 9 5.00 Very Low Very Low Very Low
Pain 6 5.00 Very Low Very Low Very Low
Disease Link Frequency Relevance Heat
Viremia 72 99.96 Very High Very High Very High
Disease Progression 90 97.72 Very High Very High Very High
Acquired Immune Deficiency Syndrome Or Hiv Infection 531 97.60 Very High Very High Very High
Opportunistic Infections 26 97.46 Very High Very High Very High
Death 35 97.36 Very High Very High Very High
Infection 216 95.28 Very High Very High Very High
Immune Reconstitution Inflammatory Syndrome 78 77.76 Quite High
Parasitic Infection 13 76.80 Quite High
Immunodeficiency 7 71.04 Quite High
Infertility 10 66.44 Quite High

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
Attitudes of citizens toward ART
Regulation (citizens) of ART
1) Confidence 0.39 Published 2006 Journal BMC Med Ethics Section Body Doc Link PMC1481581 Disease Relevance 0.07 Pain Relevance 0
But many patients said that they were given information regarding ART and its side effects at the ART clinics.
Regulation (effects) of ART
2) Confidence 0.34 Published 2010 Journal BMC Public Health Section Body Doc Link PMC2978153 Disease Relevance 0 Pain Relevance 0
The author intends to continue to research changes in the direction of court judgements on ART, changes in the consciousness of the people toward ART, and future deliberations by government and non-governmental bodies.


Regulation (changes) of ART
3) Confidence 0.24 Published 2006 Journal BMC Med Ethics Section Body Doc Link PMC1481581 Disease Relevance 0 Pain Relevance 0
We first reviewed the national Care and Treatment plan (CTP) for 2004–2009 including the ART output targets and the number of new Care and Treatment Centres (CTCs) that are to be accredited for scaling-up of access to ART.
Regulation (targets) of ART
4) Confidence 0.23 Published 2009 Journal PLoS ONE Section Body Doc Link PMC2667213 Disease Relevance 0.09 Pain Relevance 0
Our results indicate that substitutions of the second and third extracellular loops of the MC4R with homologous domains of the MC1R dramatically decreased AGRP 87-132 binding affinity, but did not affect AGRP 110-117 binding affinity.
Neg (not) Regulation (affect) of AGRP
5) Confidence 0.23 Published 2003 Journal Mol. Pharmacol. Section Abstract Doc Link 12815165 Disease Relevance 0 Pain Relevance 0.12
Substitutions of the extracytoplasmic NH2 terminus and the first extracytoplasmic loop (exoloop) of the MC4R with homologous domains of the MC1R had no effect on AGRP (87-132) binding affinity or inhibitory activity (the ability to inhibit melanocortin-stimulated cAMP generation).
Neg (no) Regulation (effect) of AGRP
6) Confidence 0.23 Published 1999 Journal J. Biol. Chem. Section Abstract Doc Link 10318826 Disease Relevance 0 Pain Relevance 0.12
Notably, these studies either stratified by or controlled for ART use, and the measurement of alcohol use was more detailed than in the previous studies.
Regulation (controlled) of ART associated with alcohol
7) Confidence 0.15 Published 2010 Journal Curr HIV/AIDS Rep Section Body Doc Link PMC2938419 Disease Relevance 0.72 Pain Relevance 0.26
These findings elevate the importance of attempting to control for ART adherence in examining the biological impact of alcohol on HIV disease progression apart from its impact on adherence.
Regulation (control) of ART associated with acquired immune deficiency syndrome or hiv infection, disease progression and alcohol
8) Confidence 0.15 Published 2010 Journal Curr HIV/AIDS Rep Section Body Doc Link PMC2938419 Disease Relevance 1.13 Pain Relevance 0.37
The effectiveness of the two-drug (PMPA/FTC) ART in reducing viral load suggests the usefulness of this model for similar studies in the future.
Regulation (effectiveness) of ART
9) Confidence 0.15 Published 2010 Journal PLoS ONE Section Body Doc Link PMC2943484 Disease Relevance 0.72 Pain Relevance 0
Some have also demonstrated vaccine-induced immune responses, but no control of post-ART viremia [43], [67].
Neg (no) Regulation (control) of ART associated with viremia
10) Confidence 0.09 Published 2010 Journal PLoS ONE Section Body Doc Link PMC2943484 Disease Relevance 0.65 Pain Relevance 0.03
The effectiveness of ART was clearly evident in the longitudinal treatment series.
Regulation (effectiveness) of ART
11) Confidence 0.03 Published 2005 Journal BMC Infect Dis Section Body Doc Link PMC1299327 Disease Relevance 0.33 Pain Relevance 0
These may include: (a) the clinical manifestation or pattern of progression of an opportunistic infection that is unusual; (b) a temporal relationship with ART initiation; (c) exclusion of alternative explanations; (d) demonstrated efficacy of ART (e.g. reduction in viral load or rise in CD4 cell count; (e) evidence of improved CD4 cell function (e.g. development of a positive tuberculin skin test); and (f) histopathology consistent with the diagnosis.
Regulation (efficacy) of ART in skin associated with opportunistic infections
12) Confidence 0.02 Published 2006 Journal Parasite Immunology Section Body Doc Link PMC1636681 Disease Relevance 1.23 Pain Relevance 0

General Comments

This test has worked.

Personal tools
Namespaces

Variants
Actions
Navigation
Toolbox