INT81842

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Context Info
Confidence 0.02
First Reported 1999
Last Reported 1999
Negated 0
Speculated 0
Reported most in Abstract
Documents 1
Total Number 2
Disease Relevance 0.44
Pain Relevance 0.62

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

signal transducer activity (Olr1106)
Anatomy Link Frequency
brain 1
Olr1106 (Rattus norvegicus)
Pain Link Frequency Relevance Heat
Eae 2 97.96 Very High Very High Very High
anesthesia 6 91.44 High High
Potency 2 89.72 High High
agonist 4 85.04 High High
Disease Link Frequency Relevance Heat
Anxiety Disorder 4 99.48 Very High Very High Very High
Hypersomnia 2 86.92 High High

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
These findings indicate that DAA1097 and DAA1106 are PBR selective ligands with potent anxiolytic-like properties, in laboratory animals.
DAA1106 Binding (ligands) of associated with anxiety disorder
1) Confidence 0.02 Published 1999 Journal Life Sci. Section Abstract Doc Link 10321725 Disease Relevance 0.27 Pain Relevance 0.34
In contrast, DAA1097 and DAA1106 did not inhibit [3H]-flunitrazepam, the central benzodiazepine receptor (CBR) ligand, binding to membranes of rat whole brain (IC50>10,000nM).
DAA1106 Binding (binding) of in brain
2) Confidence 0.02 Published 1999 Journal Life Sci. Section Abstract Doc Link 10321725 Disease Relevance 0.17 Pain Relevance 0.28

General Comments

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