INT81887

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Context Info
Confidence 0.28
First Reported 1999
Last Reported 2006
Negated 0
Speculated 0
Reported most in Abstract
Documents 9
Total Number 9
Disease Relevance 1.28
Pain Relevance 2.13

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

plasma membrane (Plvap) cytoplasm (Plvap)
Anatomy Link Frequency
neurons 5
lamina 2
PV1 1
spinal trigeminal nucleus 1
Plvap (Rattus norvegicus)
Pain Link Frequency Relevance Heat
Dorsal horn 35 99.48 Very High Very High Very High
Pain 7 97.48 Very High Very High Very High
Dorsal horn neuron 7 96.84 Very High Very High Very High
Kinase C 14 90.20 High High
Neuropeptide 1 71.44 Quite High
imagery 1 55.00 Quite High
Enkephalin 1 25.00 Low Low
pain flank 1 5.00 Very Low Very Low Very Low
Disease Link Frequency Relevance Heat
Hematuria 55 97.76 Very High Very High Very High
Pain 7 97.48 Very High Very High Very High
Syndrome 45 84.56 Quite High
Obesity 1 36.64 Quite Low
Nociception 7 5.00 Very Low Very Low Very Low
Proteinuria 4 5.00 Very Low Very Low Very Low
Kidney Stones 3 5.00 Very Low Very Low Very Low
Urolithiasis 3 5.00 Very Low Very Low Very Low
Urinary Tract Infection 2 5.00 Very Low Very Low Very Low
Renal Disease 2 5.00 Very Low Very Low Very Low

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
Neurons co-expressing CB/PKCgamma, CR/PKCgamma and PV/PKCgamma were also mainly found in lamina II, while in lamina I and lamina III, only a few neurons co-expressing CB/PKCgamma, CR/PKCgamma and PV/PKCgamma were encountered.
Gene_expression (expressing) of PV in lamina
1) Confidence 0.28 Published 2002 Journal Neurosignals Section Abstract Doc Link 12077482 Disease Relevance 0.07 Pain Relevance 0.34
Most of these neurons co-expressing CB/PKCgamma, CR/PKCgamma and PV/PKCgamma were small (</=15 microm) and medium-sized (16-35 microm) neurons and had round, triangular or fusiform-shaped cell bodies; large (>/=36 microm) multipolar neurons were infrequently seen.
Gene_expression (expressing) of PV in neurons
2) Confidence 0.28 Published 2002 Journal Neurosignals Section Abstract Doc Link 12077482 Disease Relevance 0 Pain Relevance 0.21
The present results indicate that there are some neurons co-expressing CB/PKCgamma, CR/PKCgamma and PV/PKCgamma in the medullary dorsal horn.
Gene_expression (expressing) of PV in neurons associated with dorsal horn
3) Confidence 0.28 Published 2002 Journal Neurosignals Section Abstract Doc Link 12077482 Disease Relevance 0 Pain Relevance 0.18
The percentages of neurons co-expressing PV/PKCgamma in the total numbers of PV- and PKCgamma-immunoreactive neurons were 25.7 and 4.1%, respectively.
Gene_expression (co-expressing) of PV in neurons
4) Confidence 0.25 Published 2002 Journal Neurosignals Section Abstract Doc Link 12077482 Disease Relevance 0.06 Pain Relevance 0.29
Neurons co-expressing CB/PKCgamma, CR/PKCgamma and PV/PKCgamma were also mainly found in lamina II, while in lamina I and lamina III, only a few neurons co-expressing CB/PKCgamma, CR/PKCgamma and PV/PKCgamma were encountered.
Gene_expression (expressing) of PV in lamina
5) Confidence 0.25 Published 2002 Journal Neurosignals Section Abstract Doc Link 12077482 Disease Relevance 0.08 Pain Relevance 0.36
Calbindin-D28k (CB), calretinin (CR) and parvalbumin (PV) are the most commonly expressed calcium-binding proteins and are located abundantly in the medullary dorsal horn (also called the caudal subnucleus of the spinal trigeminal nucleus).
Gene_expression (expressed) of PV in spinal trigeminal nucleus associated with dorsal horn
6) Confidence 0.25 Published 2002 Journal Neurosignals Section Abstract Doc Link 12077482 Disease Relevance 0.10 Pain Relevance 0.38
The percentages of neurons co-expressing PV/PKCgamma in the total numbers of PV- and PKCgamma-immunoreactive neurons were 25.7 and 4.1%, respectively.
Gene_expression (co-expressing) of PV in neurons
7) Confidence 0.19 Published 2002 Journal Neurosignals Section Abstract Doc Link 12077482 Disease Relevance 0.06 Pain Relevance 0.29
The present study seeks to further characterize GP subpopulations by determining whether the PPE+ GP neurons express parvalbumin immunoreactivity (PV-IR) and where their axons project by retrogradely labeling pallidal neurons with the tracer FluoroGold (FG).
Gene_expression (express) of PV-IR in neurons
8) Confidence 0.08 Published 1999 Journal Neurosci. Lett. Section Abstract Doc Link 10327165 Disease Relevance 0 Pain Relevance 0.04
The PV2 (P=0.003) and PV2/PV1 ratios (P=0.003) were significantly higher and had a wider distribution (Fig. 2) in children with hematuria than in normal children.
Gene_expression (higher) of PV1 in PV1 associated with hematuria
9) Confidence 0.01 Published 2006 Journal Eur J Pediatr Section Body Doc Link PMC1829442 Disease Relevance 0.92 Pain Relevance 0.03

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