INT81908

Context Info Confidence 0.36 First Reported 1999 Last Reported 2008 Negated 0 Speculated 0 Reported most in Body Documents 3 Total Number 3 Disease Relevance 1.27 Pain Relevance 0.31

cytosol (FDPS) mitochondrion (FDPS) small molecule metabolic process (FDPS) nucleolus (FDPS) nucleus (FDPS) cytoplasm (FDPS)

Anatomy Link Frequency plasma 1 FDPS (Homo sapiens)

Pain Link Frequency Relevance Heat Potency 2 87.36 tolerance 26 83.04 Angina 4 75.00 Inflammation 54 50.00 metalloproteinase 2 32.00 cytokine 27 5.00 Arthritis 10 5.00 Inflammatory response 8 5.00 Inflammatory marker 3 5.00 Pain 3 5.00

Disease Link Frequency Relevance Heat Myocardial Infarction 9 96.52 Acute Coronary Syndrome 6 94.04 Impaired Glucose Tolerance 26 83.04 Thrombosis Related Under Development 4 75.00 Cv General 3 Under Development 4 75.00 Diabetes Mellitus 75 73.12 INFLAMMATION 68 50.00 Aging 22 50.00 Body Weight 5 35.68 Atherosclerosis 44 5.00

Sentences Mentioned In

Key:

Protein

Mutation

Event

Anatomy

Negation

Speculation

Pain term

Disease term

Increases in plasma concentrations of cross-linked fibrin degradation products (XL-FDPs), which reflect increased fibrin turn-over, are a marker of risk for complications of myocardial infarction.

FDPs Binding (cross-linked) of in plasma associated with myocardial infarction

1) Confidence 0.36 Published 1999 Journal Int. J. Cardiol. Section Abstract Doc Link 10328612 Disease Relevance 0.79 Pain Relevance 0.07

Statistical analyses were based on ITT for BDPPI and FDPS and on completers for FDPS and GGTS.

FDPS Binding (completers) of

2) Confidence 0.29 Published 2008 Journal Diabetes Care Section Body Doc Link PMC2584172 Disease Relevance 0.48 Pain Relevance 0.15

Inhibition of FPP synthase prevents the formation of FPP and its derivative GGPP.

FPP Binding (formation) of

3) Confidence 0.04 Published 2007 Journal Immun Ageing Section Body Doc Link PMC1845171 Disease Relevance 0 Pain Relevance 0.09

General Comments

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