INT82038

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Context Info
Confidence 0.02
First Reported 1999
Last Reported 1999
Negated 0
Speculated 0
Reported most in Abstract
Documents 1
Total Number 1
Disease Relevance 0
Pain Relevance 0.64

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

cytosol (Akr1d1, Ppp1r1b) cytoplasm (Akr1d1, Ppp1r1b) oxidoreductase activity (Akr1d1)
nucleus (Ppp1r1b) intracellular (Ppp1r1b)
Akr1d1 (Rattus norvegicus)
Ppp1r1b (Rattus norvegicus)
Pain Link Frequency Relevance Heat
MU agonist 1 98.64 Very High Very High Very High
agonist 4 94.16 High High
Kappa opioid receptor 1 91.16 High High
adenocard 2 85.84 High High
Dopamine 3 83.00 Quite High
projection neuron 1 75.00 Quite High
opioid receptor 1 75.00 Quite High
mu opioid receptor 1 72.88 Quite High
Delta opioid receptors 1 65.68 Quite High
Enkephalin 2 48.80 Quite Low

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Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
The results show that, at low concentrations (100 pm-1 nm), the mu-opioid agonist, Tyr-D-Ala-Gly-N-Me-Phe-glycinol (DAMGO), inhibits the increase in DARPP-32 phosphorylation induced by activation of D1, but not by activation of A2A receptors.
Positive_regulation (activation) of D1 Positive_regulation (induced) of Phosphorylation (phosphorylation) of DARPP-32 associated with mu agonist
1) Confidence 0.02 Published 1999 Journal Eur. J. Neurosci. Section Abstract Doc Link 10336688 Disease Relevance 0 Pain Relevance 0.64

General Comments

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