INT82128

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Context Info
Confidence 0.18
First Reported 1999
Last Reported 1999
Negated 0
Speculated 0
Reported most in Abstract
Documents 1
Total Number 1
Disease Relevance 1.32
Pain Relevance 0.55

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

signal transduction (Adra2a) plasma membrane (Adra2a) cytoplasm (Adra2a)
signal transducer activity (Adra2a)
Adra2a (Rattus norvegicus)
Pain Link Frequency Relevance Heat
Clonidine 1 87.52 High High
Pain 2 81.68 Quite High
monoamine 1 80.44 Quite High
Hyperalgesia 1 76.24 Quite High
allodynia 1 75.56 Quite High
Spontaneous pain 1 75.12 Quite High
Spinal cord 1 75.00 Quite High
Disease Link Frequency Relevance Heat
Diabetes Mellitus 9 99.28 Very High Very High Very High
Nociception 1 85.04 High High
Congenital Anomalies 2 83.16 Quite High
Pain 3 81.68 Quite High
Neuropathic Pain 2 77.56 Quite High
Hyperalgesia 1 76.24 Quite High

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
The density of [3H] p-aminoclonidine binding sites and the level of expression of mRNA encoding for alpha2A-adrenoceptor subtype were also reduced as a function of diabetes.
Negative_regulation (reduced) of Transcription (expression) of alpha2A-adrenoceptor associated with diabetes mellitus
1) Confidence 0.18 Published 1999 Journal Brain Res. Section Abstract Doc Link 10350553 Disease Relevance 1.32 Pain Relevance 0.55

General Comments

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