INT82169

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Context Info
Confidence 0.31
First Reported 1999
Last Reported 2010
Negated 0
Speculated 1
Reported most in Body
Documents 2
Total Number 3
Disease Relevance 0.69
Pain Relevance 0.08

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

extracellular space (S100b) nucleus (S100b) cytoplasm (S100b)
S100b (Rattus norvegicus)
Pain Link Frequency Relevance Heat
palliative 1 75.92 Quite High
anesthesia 2 10.00 Low Low
Disease Link Frequency Relevance Heat
Metastasis 1 99.58 Very High Very High Very High
Cancer 2 89.36 High High
Skin Cancer 5 75.00 Quite High
Disease 1 60.04 Quite High
Brain Ischemia 2 50.56 Quite High
Hypoxia 2 50.00 Quite Low
Brain Injury 1 5.00 Very Low Very Low Very Low

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
Patients who responded to treatment (stable or regressing metastatic disease) showed constant or declining S100B levels in 38 of 40 patients (95%) at the interim analysis, at 8 weeks this was further increased to 39 of 40 patients (98%; P < 0.001).
Negative_regulation (declining) of S100B associated with metastasis
1) Confidence 0.31 Published 1999 Journal Br. J. Dermatol. Section Abstract Doc Link 10354072 Disease Relevance 0.64 Pain Relevance 0.08
A negative correlation of both lactate/creatinine ratio on day 1 and S100B level on days 1-3 after birth with the NBNA score was identified on days 3, 7 and 14 after birth.
Negative_regulation (correlation) of S100B
2) Confidence 0.30 Published 2010 Journal Neonatology Section Body Doc Link 19590245 Disease Relevance 0.05 Pain Relevance 0
HES130/0.4 lowers the S100B protein levels from the beginning of CPB to one hour after the termination of CPB with the probable mechanism of improving the cerebral metabolism of oxygen. 6%HES130/0.4 as priming solution may play a protective role in reduction of cerebral injury during CPB and open cardiac surgery.


Spec (probable) Negative_regulation (lowers) of S100B
3) Confidence 0.08 Published 2007 Journal Zhonghua Yi Xue Za Zhi Section Body Doc Link 17923015 Disease Relevance 0 Pain Relevance 0

General Comments

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